Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768450 | 0.87 | GABBR2 (0.42) | NFE2L2HRH3HPGDPTGESGABBR2 | |
| SCHEMBL8961311 | 0.83 | ITGB3 (0.47) | NFE2L2HRH3HPGDPTGESHDAC1 | |
| SCHEMBL16582474 | 0.82 | NFE2L2 (0.53) | NFE2L2HRH3HPGDPTGESHDAC1 | |
| SCHEMBL8767748 | 0.81 | NFE2L2 (0.44) | NFE2L2HRH3HPGDPTGESHDAC1 | |
| SCHEMBL8767164 | 0.81 | NFE2L2 (0.44) | NFE2L2HRH3HPGDPTGESHDAC1 | |
| SCHEMBL8961327 | 0.80 | CNR1 (0.40) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8768425 | 0.78 | ESR2 (0.42) | KDM4EALDH1A1POLB | |
| SCHEMBL8768434 | 0.78 | ESR2 (0.42) | KDM4EALDH1A1POLB | |
| SCHEMBL12952965 | 0.78 | NFE2L2 (0.40) | NFE2L2HRH3HPGDGABBR2GABBR1 | |
| SCHEMBL8767890 | 0.78 | GABBR2 (0.42) | HRH3HPGDHDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789067-A1 | Cyclopentyl derivatives useful as liquid crystals | Rolic AG (CH) | 1997-08-13 | — | — | EP | disclosed |