Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 4/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 2/20 | 0.30 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943204 | 0.78 | TAS1R3 (0.36) | GABRA1GABRB2POLBMEN1KMT2A | |
| SCHEMBL11333301 | 0.74 | HSD17B10 (0.46) | PTGDRPTGDR2GABRA1GABRB2POLB | |
| SCHEMBL249746 | 0.74 | IDO1 (0.54) | PTGDRPTGDR2POLBMAPTALDH1A1 | |
| SCHEMBL30956678 | 0.74 | IDO1 (0.54) | PTGDRPTGDR2POLBMAPTALDH1A1 | |
| SCHEMBL28227965 | 0.73 | MTNR1A (0.44) | GABRA1GABRB2POLBMAPTALDH1A1 | |
| SCHEMBL11228437 | 0.73 | HSD17B10 (0.42) | ALDH1A1TDP1KMT2ACYP3A4 | |
| Bromide SCHEMBL28225209 | 0.72 | IDO1 (0.52) | PTGDRPTGDR2POLBMAPTALDH1A1 | |
| SCHEMBL8191483 | 0.72 | ALDH1A1 (0.44) | GABRA1GABRB2POLBMAPTALDH1A1 | |
| SCHEMBL28227159 | 0.71 | XDH (0.44) | GABRA1GABRB2POLBMAPTALDH1A1 | |
| SCHEMBL8765889 | 0.71 | POLB (0.49) | PTGDRPTGDR2GABRA1GABRB2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0619303-B1 | 4-alkyl-3-chloro-benzenesulfinic acids, 4-alkyl-3-chloro-benzenesulfonic acids, 4-alkyl-3-chloro-alkylsulfonylbenzenes and process for their preparation | HOECHST AG (DE) | 1997-08-13 | — | — | EP | disclosed |
| EP-0619303-A1 | 4-alkyl-3-chloro-benzenesulfinic acids, 4-alkyl-3-chloro-benzenesulfonic acids, 4-alkyl-3-chloro-alkylsulfonylbenzenes and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-12 | — | — | EP | disclosed |