Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16352314 | 0.90 | LMNA (0.56) | LMNASMN1; SMN2HSD11B1ESR1MAOB | |
| SCHEMBL8766728 | 0.90 | LMNA (0.56) | LMNASMN1; SMN2HSD11B1ESR1MAOB | |
| SCHEMBL12276579 | 0.84 | SMN1; SMN2 (0.65) | LMNASMN1; SMN2HSD11B1ESR1KMT2A | |
| SCHEMBL12040557 | 0.83 | LMNA (0.57) | LMNASMN1; SMN2HSD11B1MAOBMAOA | |
| SCHEMBL25458202 | 0.80 | GRIN2D (0.64) | LMNAHSD11B1PGRALDH1A1GRIN2D | |
| SCHEMBL822923 | 0.79 | LMNA (0.57) | LMNASMN1; SMN2HSD11B1ESR1PGR | |
| SCHEMBL31525726 | 0.79 | MAOB (0.55) | LMNASMN1; SMN2HSD11B1MAOBMAOA | |
| SCHEMBL12936217 | 0.78 | KMT2A (0.66) | LMNASMN1; SMN2HSD11B1ALDH1A1KMT2A | |
| SCHEMBL12780752 | 0.74 | ESR1 (0.36) | LMNASMN1; SMN2HSD11B1ESR1PGR | |
| SCHEMBL17855983 | 0.73 | HSD11B1 (0.44) | LMNASMN1; SMN2HSD11B1ESR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120130041-A1 | Transparent Polyarylene Ether Polymer With High Heat Resistance And Method For Preparing The Same | IUCF-HYU (Industry-University Coperation Foundatio Hanyang University (KR) | 2012-05-24 | — | — | US | disclosed |