Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27758728 | 0.83 | RORC (0.40) | TSHRRORCCA1CA2CYP1A2 | |
| SCHEMBL11609816 | 0.80 | GSR (0.38) | TSHRRORCCYP1A2ALDH1A1GAA | |
| SCHEMBL930890 | 0.77 | TSHR (0.53) | TSHRRORCGABRA1GABRB2HPGD | |
| SCHEMBL1927985 | 0.75 | GABRA1 (0.52) | TSHRGABRA1GABRB1GABRB2CA1 | |
| SCHEMBL10946690 | 0.74 | CA1 (0.58) | TSHRRORCGABRA1GABRB1GABRB2 | |
| SCHEMBL560318 | 0.74 | TSHR (0.68) | TSHRRORCGABRA1GABRB1GABRB2 | |
| SCHEMBL202738 | 0.74 | TSHR (0.68) | TSHRRORCGABRA1GABRB1GABRB2 | |
| SCHEMBL561299 | 0.74 | TSHR (0.68) | TSHRRORCGABRA1GABRB1GABRB2 | |
| SCHEMBL560346 | 0.74 | TSHR (0.68) | TSHRRORCGABRA1GABRB1GABRB2 | |
| SCHEMBL6943323 | 0.73 | TSHR (0.48) | TSHRRORCGABRA1GABRB1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559079-B1 | Substituted aminophosphonate derivatives, process for their preparation and pharmaceutical compositions containing them | SYMPHAR SA (CH) | 1997-08-13 | — | — | EP | disclosed |
| US-5424303-A | For treating hypercholesterolemia and hyperlipidemia | SYMPHAR SA (CH) | 1995-06-13 | — | — | US | disclosed |
| US-5256488-A | Ethylene-vinyl ester or ethylene-alkyl acrylate copolymer, pentaerythritol thiopropionate, and hindered phenol | QUANTUM CHEMICAL CORPORATION (US) | 1993-10-26 | — | — | US | disclosed |
| EP-0559079-A1 | Substituted aminophosphonate derivatives, process for their preparation and pharmaceutical compositions containing them | SYMPHAR S.A. (CH) | 1993-09-08 | — | — | EP | disclosed |
| US-4098760-A | NON-MIGRATORY, NON-LEACHING | UNIROYAL, INC. (US) | 1978-07-04 | — | — | US | disclosed |
| US-3957892-A | A CONJUGATED DIENE AND A PHENOL | ETHYL CORPORATION (US) | 1976-05-18 | — | — | US | disclosed |