Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 7/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10534421 | 0.85 | GABRA1 (0.39) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL28075126 | 0.84 | GABRA1 (0.45) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL11655349 | 0.80 | CA2 (0.35) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL11812194 | 0.77 | GABRA1 (0.33) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL8766765 | 0.75 | TSHR (0.48) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL3246655 | 0.74 | CA1 (0.31) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL6543970 | 0.72 | — | — | |
| SCHEMBL930755 | 0.70 | GABRA1 (0.48) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL275427 | 0.69 | CA1 (1.00) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL1760529 | 0.69 | CA1 (0.70) | GABRA1GABRB1GABRB2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105849088-B | Pharmacologically active compounds | 利物浦大学 | 2020-07-03 | — | — | CN | claimed |
| CN-105849088-A | Pharmacologically active compounds | 利物浦大学 | 2016-08-10 | — | — | CN | claimed |
| US-5292956-A | For lubricants, mineral oils, polypropylene | ETHYL CORPORATION (US) | 1994-03-08 | — | — | US | claimed |
| EP-0565135-A1 | Known and selected novel arylmethylenyl derivatives of imidazolidinones useful as antiallergy agents and antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1993-10-13 | — | — | EP | claimed |
| EP-0343643-A2 | Arylmethylenyl derivatives of thiazolidnones, imidazolidinones and oxazolidinones useful as antiallergy agents and antiinflamatory agents | WARNER-LAMBERT COMPANY (US) | 1989-11-29 | — | — | EP | claimed |
| CN-114149311-B | Method for preparing 4-hydroxybenzophenone compound by taking p-methylene quinone as substrate | 上海应用技术大学 | 2023-11-03 | — | — | CN | disclosed |
| CN-114149311-A | Method for preparing 4-hydroxybenzophenone compound by taking p-methylenequinone as substrate | 上海应用技术大学 | 2022-03-08 | — | — | CN | disclosed |
| CN-105849088-B | Pharmacologically active compounds | 利物浦大学 | 2020-07-03 | — | — | CN | disclosed |
| US-10442814-B2 | Pharmacologically active compounds | UNIVERSITY OF LIVERPOOL (GB) | 2019-10-15 | — | — | US | disclosed |
| US-20190084993-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2019-03-21 | — | — | US | disclosed |
| US-9631048-B2 | Sulfonium compounds, their preparation and use | BASF SE (DE) | 2017-04-25 | — | — | US | disclosed |
| CN-104379628-B | Sulfonium compound, it prepares and application thereof | 巴斯夫欧洲公司 | 2016-11-16 | — | — | CN | disclosed |
| US-4734519-A | STABILIZERS | MALLINCKRODT, INC. (US) | 1988-03-29 | — | — | US | disclosed |
| EP-0250087-A1 | Pentaerythritol co-esters | MALLINCKRODT, INC. (US) | 1987-12-23 | — | — | EP | disclosed |
| EP-0032586-B1 | DURABLE POLYESTER MOLDING COMPOSITION | GAF CORPORATION (US) | 1984-01-11 | — | — | EP | disclosed |
| US-4277391-A | CONTAINING THREE DIFFERENT TYPES OF ANTIOXIDANTS | GAF CORPORATION (US) | 1981-07-07 | — | — | US | disclosed |
| US-4098760-A | NON-MIGRATORY, NON-LEACHING | UNIROYAL, INC. (US) | 1978-07-04 | — | — | US | disclosed |
| US-4076814-A | DITHIOCARBAMIC ACID DERIVATIVES | SANKYO COMPANY LIMITED (JA) | 1978-02-28 | — | — | US | disclosed |
| US-3957920-A | ANTIOXIDANTS | CIBA-GEIGY CORPORATION (US) | 1976-05-18 | — | — | US | disclosed |
| US-3957892-A | A CONJUGATED DIENE AND A PHENOL | ETHYL CORPORATION (US) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10442814-B2 | Pharmacologically active compounds | GRIN1, OPRL1, OPRK1 | GABRA1 216/4885GABRB1 217/4885GABRB2 317/4885 |
| US-20190084993-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS | GRIN1, OPRL1, OPRK1 | GABRA1 216/4885GABRB1 217/4885GABRB2 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.