Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.79 |
| ▸ | MAPT | P10636 | 5/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.79 |
| ▸ | MEN1 | O00255 | 3/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | PKM | P14618 | 1/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32689398 | 0.95 | ALDH1A1 (0.75) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30419025 | 0.86 | PKM (1.00) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL361312 | 0.86 | PKM (1.00) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL17385260 | 0.83 | ALDH1A1 (0.59) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL12966475 | 0.83 | SMN1; SMN2 (0.67) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5489025 | 0.82 | SMN1; SMN2 (0.77) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL17378169 | 0.82 | KDM4E (0.67) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| Indole-3-Acetic Acid SCHEMBL7048296 | 0.81 | PKM (0.89) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL20657329 | 0.81 | MTNR1A (0.55) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL29466101 | 0.80 | PKM (0.73) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787134-A1 | IMPROVEMENTS IN OR RELATING TO STEREOSELECTIVE SYNTHESES | OXFORD ASYMMETRY LIMITED (GB) | 1997-08-06 | — | — | EP | disclosed |
| WO-1996012726-A1 | IMPROVEMENTS IN OR RELATING TO STEREOSELECTIVE SYNTHESES | OXFORD ASYMMETRY LIMITED (GB) | 1996-05-02 | — | — | WO | disclosed |