Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766400 | 0.88 | DRD2 (0.38) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL8766539 | 0.87 | HTT (0.37) | NPY1RACHEOPRM1OPRD1OPRK1 | |
| SCHEMBL8766434 | 0.85 | OPRK1 (0.39) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL8766440 | 0.82 | HRH3 (0.39) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL8766242 | 0.82 | ESR1 (0.41) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL8766347 | 0.81 | CYP3A4 (0.36) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL8767246 | 0.80 | CYP3A4 (0.38) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL8766579 | 0.80 | CYP3A4 (0.38) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL8766430 | 0.80 | CYP3A4 (0.38) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL8766953 | 0.75 | CCR2 (0.42) | ACHEOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601813-B1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5382688-A | Diamino compounds and their production method | CHISSO CORPORATION (JP) | 1995-01-17 | — | — | US | disclosed |
| EP-0601813-A1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1994-06-15 | — | — | EP | disclosed |