Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766871 | 0.87 | DRD2 (0.41) | HTTNPY1RACHEOPRM1OPRD1 | |
| SCHEMBL8767257 | 0.87 | SMN1; SMN2 (0.36) | SMN1; SMN2DDB1CRBNHCAR3HCAR2 | |
| SCHEMBL8766387 | 0.83 | OPRK1 (0.39) | SMN1; SMN2DDB1CRBNHCAR3HCAR2 | |
| SCHEMBL8766459 | 0.81 | ESR1 (0.43) | HCAR3HCAR2ACHETP53L3MBTL1 | |
| SCHEMBL8766392 | 0.80 | HRH3 (0.37) | SMN1; SMN2DDB1CRBNHCAR3HCAR2 | |
| SCHEMBL8766487 | 0.79 | HRH3 (0.34) | SMN1; SMN2DDB1CRBNHCAR3HCAR2 | |
| SCHEMBL8766518 | 0.78 | KCNH2 (0.35) | DDB1CRBNHCAR3HCAR2SIGMAR1 | |
| SCHEMBL8767096 | 0.78 | KCNH2 (0.35) | DDB1CRBNHCAR3HCAR2SIGMAR1 | |
| SCHEMBL8766290 | 0.78 | KCNH2 (0.35) | DDB1CRBNHCAR3HCAR2SIGMAR1 | |
| SCHEMBL8766953 | 0.77 | CCR2 (0.42) | ACHEOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601813-B1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5382688-A | Diamino compounds and their production method | CHISSO CORPORATION (JP) | 1995-01-17 | — | — | US | disclosed |
| EP-0601813-A1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1994-06-15 | — | — | EP | disclosed |