Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1374797 | 0.88 | PPARA (0.52) | L3MBTL1PPARANPSR1PPARGCTSS | |
| SCHEMBL1374794 | 0.88 | PPARA (0.52) | L3MBTL1PPARANPSR1PPARGCTSS | |
| SCHEMBL6318931 | 0.88 | PPARA (0.52) | L3MBTL1PPARANPSR1PPARGCTSS | |
| Cyclohexylamine SCHEMBL9751744 | 0.83 | ITGB3 (0.44) | L3MBTL1PPARAPPARGCTSSTRPM8 | |
| SCHEMBL29097327 | 0.79 | PPARA (0.44) | L3MBTL1PPARANPSR1PPARGCTSS | |
| SCHEMBL29097329 | 0.79 | PPARA (0.44) | L3MBTL1PPARANPSR1PPARGCTSS | |
| SCHEMBL22982847 | 0.78 | L3MBTL1 (0.47) | L3MBTL1PPARAHTR2CSLC6A4NPSR1 | |
| SCHEMBL1414516 | 0.78 | PPARA (0.49) | L3MBTL1PPARANPSR1PPARGCTSS | |
| SCHEMBL1414518 | 0.78 | PPARA (0.49) | L3MBTL1PPARANPSR1PPARGCTSS | |
| SCHEMBL6927349 | 0.78 | ITGB3 (0.46) | L3MBTL1HTR2CSLC6A4ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400065-B1 | LHRH ANALOG | TAP PHARMACEUTICALS INC (US) | 1997-08-27 | — | — | EP | disclosed |
| US-5300492-A | Suppressing levels of sex hormones in male or female mammals | TAP PHARMACEUTICALS (US) | 1994-04-05 | — | — | US | disclosed |
| US-5110904-A | Luteinizing hormone releasing hormone; suppression of sex hormones | ABBOTT LABORATORIES (US) | 1992-05-05 | — | — | US | disclosed |
| EP-0413209-A1 | LHRH analogs | TAP Pharmaceuticals Inc. (US) | 1991-02-20 | — | — | EP | disclosed |
| EP-0328090-A2 | LHRH analogs | ABBOTT LABORATORIES (US) | 1989-08-16 | — | — | EP | disclosed |