Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8767343 | 0.83 | L3MBTL1 (0.43) | ITGB3ITGA2BL3MBTL1TRPM8PPARG | |
| SCHEMBL5194032 | 0.82 | ITGB3 (0.52) | ITGB3ITGA2BL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL8710842 | 0.75 | ITGB3 (0.53) | ITGB3ITGA2BL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL21837387 | 0.74 | ITGB3 (0.47) | ITGB3ITGA2BL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL21837512 | 0.74 | ITGB3 (0.47) | ITGB3ITGA2BL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL22092025 | 0.74 | ITGB3 (0.49) | ITGB3ITGA2BL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL5192318 | 0.73 | ABCB1 (0.47) | ITGB3ITGA2BL3MBTL1ALDH1A1TSHR | |
| SCHEMBL10606737 | 0.72 | CTSK (0.39) | ITGB3ITGA2BALDH1A1PPARGCTSL | |
| SCHEMBL24821124 | 0.71 | ITGB3 (0.52) | ITGB3ITGA2BL3MBTL1ALDH1A1SIGMAR1 | |
| SCHEMBL9087894 | 0.71 | ITGB3 (0.49) | ITGB3ITGA2BL3MBTL1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400065-A4 | LHRH ANALOGS | — | 1991-03-13 | — | — | EP | disclosed |
| EP-0400065-A1 | LHRH ANALOGS. | ABBOTT LAB (US) | 1990-12-05 | — | — | EP | disclosed |
| WO-1989007450-A1 | LHRH ANALOGS | ABBOTT LABORATORIES (US) | 1989-08-24 | — | — | WO | disclosed |