Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.48 |
| ▸ | KDM1A | O60341 | 11/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2722893 | 0.79 | TRPV4 (0.52) | CYP11B1CYP11B2KCNJ1MEN1ALOX5 | |
| SCHEMBL14555723 | 0.77 | CYP11B1 (0.68) | CYP11B1CYP11B2TUBB4ATUBBTUBA3C | |
| SCHEMBL3304437 | 0.77 | CYP11B1 (0.72) | CYP11B1CYP11B2TUBB4ATUBBTUBA3C | |
| SCHEMBL8768626 | 0.73 | CYP19A1 (0.39) | CYP11B1CYP11B2MEN1POLBALOX5 | |
| SCHEMBL28880915 | 0.71 | ALDH1A1 (0.44) | MEN1POLBALOX5GAAMAPT | |
| SCHEMBL5573395 | 0.71 | CYP19A1 (0.51) | MEN1POLBALOX5GAAMAPT | |
| SCHEMBL8379621 | 0.71 | CYP11B1 (0.47) | CYP11B1CYP11B2KDM1AKCNJ1 | |
| SCHEMBL4820484 | 0.71 | CYP11B1 (0.47) | CYP11B1CYP11B2KDM1AKCNJ1 | |
| SCHEMBL5573402 | 0.70 | ESR2 (0.54) | MEN1GABRA5GABRA3CNR2KMT2A | |
| SCHEMBL4620939 | 0.70 | GABRA1 (0.41) | CYP11B1CYP11B2KDM1AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440643-B1 | FLUORINATED 4''-CYANO SUBSTITUTED TERPHENYLS | SECR DEFENCE BRIT (GB) | 1997-09-03 | — | — | EP | claimed |