Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573395 | 0.81 | CYP19A1 (0.51) | CYP19A1KDM4EGAAALDH1A1NPSR1 | |
| SCHEMBL7198375 | 0.78 | GABRA1 (0.41) | CYP19A1KDM4EGAAALDH1A1NPSR1 | |
| SCHEMBL4620939 | 0.78 | GABRA1 (0.41) | CYP19A1KDM4EGAAALDH1A1NPSR1 | |
| SCHEMBL27416538 | 0.76 | EGLN2 (0.44) | KDM4EGAAALDH1A1NPSR1HPGD | |
| SCHEMBL9274282 | 0.75 | GABRA1 (0.50) | KDM4EGAAALDH1A1NPSR1HPGD | |
| SCHEMBL29027369 | 0.74 | GABRA1 (0.34) | KDM4EGAAALDH1A1NPSR1HPGD | |
| SCHEMBL2548493 | 0.73 | MEN1 (0.44) | KDM4EGAAALDH1A1NPSR1HPGD | |
| SCHEMBL8767378 | 0.73 | CYP11B1 (0.48) | GAAMEN1MAPTGABRA1CNR1 | |
| SCHEMBL7194022 | 0.72 | PTGDR2 (0.43) | CYP19A1KDM4EGAAALDH1A1NPSR1 | |
| SCHEMBL2722893 | 0.72 | TRPV4 (0.52) | KDM4EGAAALDH1A1NPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440643-B1 | FLUORINATED 4''-CYANO SUBSTITUTED TERPHENYLS | SECR DEFENCE BRIT (GB) | 1997-09-03 | — | — | EP | claimed |