Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29797174 | 0.83 | GLA (0.59) | P2RX7GLAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL526160 | 0.83 | GLA (0.59) | P2RX7GLAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6888143 | 0.81 | POLB (0.46) | P2RX7GLAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL876740 | 0.75 | KMT2A (0.39) | P2RX7KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL21950 | 0.71 | KMT2A (0.61) | P2RX7GLAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL15286566 | 0.71 | KMT2A (0.61) | P2RX7GLAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL29356683 | 0.71 | KMT2A (0.61) | P2RX7GLAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10106053 | 0.70 | TP53 (0.48) | P2RX7GLAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL727891 | 0.70 | GLA (0.47) | P2RX7GLAMAPTSMN1; SMN2POLB | |
| SCHEMBL6901764 | 0.69 | P2RX7 (0.40) | P2RX7GLAKMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2618667-A2 | USE OF BIOLOGICAL OR CHEMICAL CONTROL AGENTS FOR CONTROLLING INSECTS AND NEMATODES IN RESISTANT CROPS | Bayer Intellectual Property GmbH (DE) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038480-A2 | USE OF BIOLOGICAL OR CHEMICAL CONTROL AGENTS FOR CONTROLLING INSECTS AND NEMATODES IN RESISTANT CROPS | BAYER CROPSCIENCE AG (DE) | 2012-03-29 | — | — | WO | disclosed |