Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL526159 | 0.82 | KMT2A (0.59) | KMT2AMEN1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL3457836 | 0.80 | PTGER4 (0.43) | KMT2AMEN1P2RX7TYK2 | |
| SCHEMBL876739 | 0.75 | P2RX7 (0.43) | KMT2AMEN1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL3456624 | 0.70 | KMT2A (0.56) | KMT2AMEN1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL6030604 | 0.70 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL6030503 | 0.70 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL6553866 | 0.68 | LMNA (0.60) | KMT2AMEN1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL16240114 | 0.68 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL3457566 | 0.68 | S1PR3 (0.40) | KMT2AMEN1BDKRB1 | |
| SCHEMBL6031138 | 0.68 | MEN1 (0.41) | KMT2AMEN1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2618667-A2 | USE OF BIOLOGICAL OR CHEMICAL CONTROL AGENTS FOR CONTROLLING INSECTS AND NEMATODES IN RESISTANT CROPS | Bayer Intellectual Property GmbH (DE) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038480-A2 | USE OF BIOLOGICAL OR CHEMICAL CONTROL AGENTS FOR CONTROLLING INSECTS AND NEMATODES IN RESISTANT CROPS | BAYER CROPSCIENCE AG (DE) | 2012-03-29 | — | — | WO | disclosed |