SCHEMBL8767393

SCHEMBL8767393

c1ccc2c(c1)-c1ccccc1-c1c3ccccc3c-2c2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
MAPK1 P28482 4/20 0.42
MAPT P10636 3/20 0.42
KDM4E B2RXH2 2/20 0.42
NPC1 O15118 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
CES2 O00748 1/20 0.42
APAF1 O14727 1/20 0.42
TERT O14746 1/20 0.42
PLIN1 O60240 1/20 0.42
TDP2 O95551 1/20 0.42
S1PR4 O95977 1/20 0.42
LMNA P02545 1/20 0.42
PLA2G1B P04054 1/20 0.42
BCHE P06276 1/20 0.42
POLB P06746 1/20 0.42
PTPRC P08575 1/20 0.42
THRB P10828 1/20 0.42
PLCG1 P19174 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4826724 0.86 ALDH1A1 (0.44) MEN1KMT2AMAPK1MAPTKDM4E
SCHEMBL5826281 0.86 HPRT1 (0.40) MEN1KMT2AMAPK1MAPTKDM4E
SCHEMBL2379478 0.84 DNMT1 (0.47) MEN1KMT2AMAPK1MAPTKDM4E
SCHEMBL260916 0.84 DNMT1 (0.47) MEN1KMT2AMAPK1MAPTKDM4E
SCHEMBL29416707 0.84 DNMT1 (0.47) MEN1KMT2AMAPK1MAPTKDM4E
SCHEMBL4762276 0.82 CRHBP (0.50) MEN1KMT2AMAPK1MAPTKDM4E
SCHEMBL701595 0.82 ALDH1A1 (0.35) MEN1KMT2AMAPK1MAPTKDM4E
SCHEMBL22419027 0.82 DHFR (0.46) MEN1KMT2AMAPK1MAPTKDM4E
Triphenylene SCHEMBL28883804 0.81 MAPK1 (0.50) MEN1KMT2AMAPK1MAPTKDM4E
Triphenylene SCHEMBL358941 0.81 MAPK1 (0.50) MEN1KMT2AMAPK1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0698335-B1 ELECTROLUMINESCENT DEVICES COMPRISING POLYMERS POLAROID CORP (US) 1997-08-27 EP disclosed
US-5571626-A Electroluminescent devices comprising polymers, and processes for their use POLAROID CORPORATION (US) 1996-11-05 US disclosed
EP-0698335-A1 ELECTROLUMINESCENT DEVICES COMPRISING POLYMERS POLAROID CORP (US) 1996-02-28 EP disclosed
US-5376456-A Electroluminescent devices comprising polymers, and processes for their use POLAROID CORPORATION (US) 1994-12-27 US disclosed
WO-1994027417-A1 ELECTROLUMINESCENT DEVICES COMPRISING POLYMERS POLAROID CORPORATION (US) 1994-11-24 WO disclosed