Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767402 | 0.94 | LMNA (0.38) | LMNATHRBALDH1A1KMT2AGAA | |
| SCHEMBL7651717 | 0.81 | TDP1 (0.43) | LMNATHRBALDH1A1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL8767266 | 0.80 | TDP1 (0.42) | LMNATHRBALDH1A1KMT2ANPC1 | |
| SCHEMBL8768611 | 0.80 | TDP1 (0.42) | LMNATHRBALDH1A1KMT2ANPC1 | |
| SCHEMBL14578736 | 0.79 | THRB (0.51) | LMNATHRBALDH1A1KMT2AOPRD1 | |
| SCHEMBL7647805 | 0.78 | LMNA (0.41) | LMNATHRBALDH1A1KMT2AKDM4E | |
| SCHEMBL8768617 | 0.78 | SMN1; SMN2 (0.41) | LMNATHRBALDH1A1KMT2ANPC1 | |
| SCHEMBL348081 | 0.76 | ALDH1A1 (0.43) | LMNAALDH1A1KMT2AGAANPC1 | |
| SCHEMBL9206601 | 0.75 | GLS (0.41) | LMNATHRBKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL16320685 | 0.75 | ALDH1A1 (0.49) | LMNAALDH1A1KMT2AGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790241-A1 | COMPLEXONES WITH THE STRUCTURE OF N-2-(AZOL-1(2)-YL)ETHYLIMINODIACETIC ACIDS, SYNTHESIS, ANALYTICAL STUDY AND BIOLOGICAL APPLICATIONS | UNIVERSIDAD NACIONAL DE EDUCACION A DISTANCIA (ES) | 1997-08-20 | — | — | EP | claimed |
| EP-0790241-A1 | COMPLEXONES WITH THE STRUCTURE OF N-2-(AZOL-1(2)-YL)ETHYLIMINODIACETIC ACIDS, SYNTHESIS, ANALYTICAL STUDY AND BIOLOGICAL APPLICATIONS | UNIVERSIDAD NACIONAL DE EDUCACION A DISTANCIA (ES) | 1997-08-20 | — | — | EP | disclosed |