Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | POLA1 | P09884 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768777 | 1.00 | DRD2 (0.54) | DRD2DRD3POLA1CYP3A4ALDH1A1 | |
| SCHEMBL3951310 | 0.89 | KDM1A (0.57) | DRD2DRD3POLA1CYP3A4ALDH1A1 | |
| SCHEMBL11290168 | 0.85 | DRD2 (0.50) | DRD2DRD3POLA1CYP3A4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11291604 | 0.83 | DRD2 (0.49) | DRD2DRD3POLA1CYP3A4ALDH1A1 | |
| SCHEMBL20366521 | 0.81 | POLA1 (0.50) | DRD2DRD3POLA1CYP3A4ALDH1A1 | |
| SCHEMBL1950165 | 0.78 | OPRM1 (0.44) | OPRM1OPRK1 | |
| SCHEMBL11297637 | 0.77 | KDM1A (0.54) | DRD2DRD3KDM1AADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL11296787 | 0.75 | KDM1A (0.52) | DRD2DRD3CYP3A4ALDH1A1KDM1A | |
| SCHEMBL17988091 | 0.74 | KDM1A (0.67) | POLA1KDM1A | |
| SCHEMBL5343873 | 0.74 | KDM1A (0.50) | MAPK1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579833-B1 | ETHANOLAMINE DERIVATIVES WITH ANTI-POLLAKIURIA ACTIVITY | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-20 | — | — | EP | disclosed |