Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | SMO | Q99835 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876437 | 0.88 | F10 (0.33) | F10CCR5MCHR1 | |
| SCHEMBL876499 | 0.87 | SLC2A1 (0.35) | F10CCR5MCHR1 | |
| SCHEMBL875680 | 0.86 | F10 (0.33) | F10CCR5MCHR1 | |
| SCHEMBL876268 | 0.80 | F10 (0.34) | F10NPC1RAB9ACCR5MCHR1 | |
| SCHEMBL878327 | 0.79 | TLR9 (0.36) | F10 | |
| SCHEMBL876159 | 0.78 | NPC1 (0.35) | F10NPC1RAB9ACCR5MCHR1 | |
| SCHEMBL876267 | 0.78 | F10 (0.36) | F10NPC1RAB9ACCR5 | |
| SCHEMBL784870 | 0.75 | F10 (0.42) | F10NPC1RAB9ACCR5 | |
| SCHEMBL784756 | 0.72 | F10 (0.40) | F10NPC1RAB9ACCR5 | |
| SCHEMBL876778 | 0.72 | BDKRB1 (0.39) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619178-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | claimed |
| EP-2619178-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | disclosed |