Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 6/20 | 0.36 |
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5030278 | 0.85 | FDPS (0.46) | LAP3FDPSMMP2MMP1CA2 | |
| SCHEMBL16163200 | 0.83 | GABBR2 (0.35) | LAP3FDPSMMP2MMP1CA2 | |
| SCHEMBL339100 | 0.81 | FOLH1 (0.38) | LAP3MMP2MMP1CA2CA12 | |
| SCHEMBL19455883 | 0.78 | FDPS (0.39) | LAP3FDPSMETAP1 | |
| SCHEMBL17488968 | 0.76 | LAP3 (0.37) | LAP3FDPSMMP2MMP1CA2 | |
| SCHEMBL316162 | 0.75 | — | — | |
| SCHEMBL19455938 | 0.75 | LAP3 (0.46) | LAP3FDPSMMP2MMP1CA2 | |
| SCHEMBL2486751 | 0.74 | — | — | |
| SCHEMBL2491379 | 0.73 | — | — | |
| SCHEMBL20606615 | 0.72 | FDPS (0.44) | LAP3FDPSMETAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017176679-A1 | DNA SEQUENCING BY SYNTHESIS WITH NUCLEOTIDE ANALOGUES AND RAMAN DETECTION | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-10-12 | — | — | WO | disclosed |
| EP-2619178-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | disclosed |