SCHEMBL339100

SCHEMBL339100

CCC(CC(=O)O)P(=O)(O)CC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.38
CA2 P00918 2/20 0.33
MMP1 P03956 2/20 0.33
MMP2 P08253 2/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
LAP3 P28838 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
MMP8 P22894 1/20 0.33
CA9 Q16790 1/20 0.33
CA4 P22748 1/20 0.32
MMP3 P08254 1/20 0.32
TDP1 Q9NUW8 2/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
BLM P54132 1/20 0.32
KMT2A Q03164 1/20 0.32
FFAR3 O14843 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL339643 0.83 FOLH1 (0.35) FOLH1CA2MMP1MMP2SLC22A6
SCHEMBL8781578 0.82 FOLH1 (0.45) FOLH1CA2MMP1MMP2SLC22A6
SCHEMBL2976107 0.82 FOLH1 (0.40) FOLH1CA2MMP1MMP2SLC22A6
SCHEMBL339732 0.82 FOLH1 (0.38) FOLH1MMP1MMP2LAP3MMP3
SCHEMBL339802 0.82 PPARD (0.35) FOLH1CA2MMP1MMP2SLC22A6
SCHEMBL876782 0.81 LAP3 (0.42) CA2MMP1MMP2LAP3CA12
SCHEMBL339431 0.80 GPR84 (0.39) CA2GPR84
SCHEMBL2982763 0.80 SLC22A6 (0.35) FOLH1CA2MMP1MMP2SLC22A6
SCHEMBL339817 0.79 LPAR3 (0.44) GPR84
Butane SCHEMBL7715957 0.78 FOLH1 (0.42) FOLH1CA2LAP3CA4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1832594-B1 Compounds of mono-carboxyl functionalised dialkylphosphine acid salts, a method for their manufacture and their application CLARIANT FINANCE BVI LTD (VG) 2011-05-18 EP claimed
EP-1832595-B1 Compounds of mono-carboxyl functionalised dialkylphosphine acid salts and other components, a method for their manufacture and their application CLARIANT FINANCE BVI LTD (VG) 2009-07-15 EP claimed
US-20070213563-A1 Mixtures composed of monocarboxy-functionalized dialkylphosphinic acid salts, their use und a process for their preparation CLARIANT INTERNATIONAL LTD 2007-09-13 US claimed
US-20070213436-A1 Mixtures composed or monocarboxy-functionalized dialkylphosphinic acids, their use and a process for their preparation CLARIANT INTERNATIONAL LTD 2007-09-13 US claimed
EP-1832594-A1 Compounds of mono-carboxyl functionalised dialkylphosphine acid salts, a method for their manufacture and their application CLARIANT INTERNATIONAL LTD. (CH) 2007-09-12 EP claimed
EP-1832595-A1 Compounds of mono-carboxyl functionalised dialkylphosphine acid salts and other components, a method for their manufacture and their application CLARIANT INTERNATIONAL LTD. (CH) 2007-09-12 EP claimed
US-8097753-B2 Mixtures composed or monocarboxy-functionalized dialkylphosphinic acids, their use and a process for their preparation CLARIANT FINANCE (BVI) LIMITED (VG) 2012-01-17 US disclosed
EP-1832594-B1 Compounds of mono-carboxyl functionalised dialkylphosphine acid salts, a method for their manufacture and their application CLARIANT FINANCE BVI LTD (VG) 2011-05-18 EP disclosed
EP-1832595-B1 Compounds of mono-carboxyl functionalised dialkylphosphine acid salts and other components, a method for their manufacture and their application CLARIANT FINANCE BVI LTD (VG) 2009-07-15 EP disclosed
US-20070213436-A1 Mixtures composed or monocarboxy-functionalized dialkylphosphinic acids, their use and a process for their preparation CLARIANT INTERNATIONAL LTD 2007-09-13 US disclosed
US-20070213563-A1 Mixtures composed of monocarboxy-functionalized dialkylphosphinic acid salts, their use und a process for their preparation CLARIANT INTERNATIONAL LTD 2007-09-13 US disclosed
EP-1832595-A1 Compounds of mono-carboxyl functionalised dialkylphosphine acid salts and other components, a method for their manufacture and their application CLARIANT INTERNATIONAL LTD. (CH) 2007-09-12 EP disclosed
EP-1832594-A1 Compounds of mono-carboxyl functionalised dialkylphosphine acid salts, a method for their manufacture and their application CLARIANT INTERNATIONAL LTD. (CH) 2007-09-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070213563-A1 Mixtures composed of monocarboxy-functionalized dialkylphosphinic acid salts, their use und a process for their preparation DBH, HBB, ALKBH3 FOLH1 4677/4885CA2 2455/4885MMP1 3928/4885
US-20070213436-A1 Mixtures composed or monocarboxy-functionalized dialkylphosphinic acids, their use and a process for their preparation PAH, ALKBH3, FTO FOLH1 2833/4885CA2 1840/4885MMP1 2850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.