Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HPN | P05981 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768745 | 0.77 | ALOX15 (0.49) | CA2CA1ALOX15HPNMAPT | |
| SCHEMBL8768706 | 0.77 | CA2 (0.49) | CA2CA1ALOX15HPNMAPT | |
| SCHEMBL9008246 | 0.73 | ESR1 (0.59) | CA2CA1ALOX15HPNMAPT | |
| Hydroquinone SCHEMBL7796131 | 0.72 | CA2 (0.84) | CA2CA1ALOX15HPNMAPT | |
| SCHEMBL8768071 | 0.70 | CA2 (0.44) | CA2CA1ALOX15HPNMAPT | |
| SCHEMBL8767332 | 0.70 | CA2 (0.44) | CA2CA1ALOX15HPNMAPT | |
| SCHEMBL8768683 | 0.68 | ESR1 (0.61) | CA2CA1ALOX15MAPTALDH1A1 | |
| SCHEMBL5827516 | 0.67 | CA2 (0.52) | CA2CA1ALOX15HPNMAPT | |
| Butylated Hydroxytoluene SCHEMBL9619750 | 0.66 | CA2 (0.82) | CA2CA1ALOX15HPNMAPT | |
| SCHEMBL15397241 | 0.66 | PTGS1 (0.50) | CA2CA1ALOX15MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621255-B1 | Substituted phenoxy-isobutyric acids and esters | ADIR (FR) | 1997-08-20 | — | — | EP | disclosed |
| EP-0621255-A1 | Substituted phenoxy-isobutyric acids and esters | ADIR ET COMPAGNIE (FR) | 1994-10-26 | — | — | EP | disclosed |