Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767412 | 0.81 | LTA4H (0.31) | — | |
| SCHEMBL8768706 | 0.79 | CA2 (0.49) | CA2CA1ALDH1A1MAPTMEN1 | |
| SCHEMBL8768787 | 0.76 | GABBR2 (0.42) | CA2CA1GABBR2GABBR1ALDH1A1 | |
| SCHEMBL8767332 | 0.74 | CA2 (0.44) | CA2CA1GABBR2GABBR1ALDH1A1 | |
| SCHEMBL8768484 | 0.71 | MAPT (0.44) | CA2CA1GABBR2GABBR1ALDH1A1 | |
| Hydroquinone SCHEMBL7796131 | 0.71 | CA2 (0.84) | CA2CA1ALDH1A1MAPTMEN1 | |
| SCHEMBL4175772 | 0.71 | MAPK1 (0.39) | CYP1A2MAPK1NPSR1POLBCYP2C9 | |
| SCHEMBL8767862 | 0.70 | CA2 (0.45) | CA2CA1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL9008246 | 0.68 | ESR1 (0.59) | CA2CA1ALDH1A1MAPTMEN1 | |
| SCHEMBL15685940 | 0.68 | CA2 (0.59) | CA2CA1GABBR2GABBR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621255-B1 | Substituted phenoxy-isobutyric acids and esters | ADIR (FR) | 1997-08-20 | — | — | EP | disclosed |
| EP-0621255-A1 | Substituted phenoxy-isobutyric acids and esters | ADIR ET COMPAGNIE (FR) | 1994-10-26 | — | — | EP | disclosed |