Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766909 | 0.89 | RAD51 (0.34) | ALDH1A1RAD51TDP1KMT2AMEN1 | |
| SCHEMBL7513100 | 0.81 | RAD51 (0.50) | ALDH1A1RAD51TDP1KMT2AMAPT | |
| SCHEMBL2791741 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TDP1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL24435585 | 0.77 | KMT2A (0.49) | KMT2AMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL8779358 | 0.77 | MAPT (0.49) | ALDH1A1TDP1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11768896 | 0.76 | KMT2A (0.49) | ALDH1A1TDP1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL3903145 | 0.76 | ALDH1A1 (0.48) | ALDH1A1RAD51TDP1KMT2AMAPT | |
| SCHEMBL6398442 | 0.76 | THRB (0.55) | ALDH1A1TDP1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL410299 | 0.76 | KMT2A (0.44) | ALDH1A1TDP1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7230864 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TDP1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1258568-C | Polymer composition and its use | BAUSCH & LOMB (US) | 2006-06-07 | — | — | CN | claimed |
| CN-1270973-A | Polymer composition and its use | BAUSCH & LOMB (US) | 2000-10-25 | — | — | CN | claimed |
| US-5449729-A | Vinyl monomer and crosslinking agent and acrylates with styrene | BAUSCH & LOMB INCORPORATED (US) | 1995-09-12 | — | — | US | claimed |
| EP-0611367-A1 | NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION. | BAUSCH & LOMB (US) | 1994-08-24 | — | — | EP | claimed |
| US-5310779-A | Compatible crosslinkers having vinyl-, acrylic-and/or styrenyl-groups to crosslink incompatible unsaturated addition monomers; contact lens; molding materials | BAUSCH & LOMB INCORPORATED (US) | 1994-05-10 | — | — | US | claimed |
| CN-1074457-A | Novel crosslinking agent capable of being cured by ultraviolet rays for copolymerization | BAUSCH & LOMB (US) | 1993-07-21 | — | — | CN | claimed |
| WO-1993009084-A1 | NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION | BAUSCH & LOMB INCORPORATED (US) | 1993-05-13 | — | — | WO | claimed |
| CN-1258568-C | Polymer composition and its use | BAUSCH & LOMB (US) | 2006-06-07 | — | — | CN | disclosed |
| CN-1063764-C | Process for preparing polymers | BAUSCH & LOMB (US) | 2001-03-28 | — | — | CN | disclosed |
| CN-1270973-A | Polymer composition and its use | BAUSCH & LOMB (US) | 2000-10-25 | — | — | CN | disclosed |
| EP-0611367-B1 | NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION | BAUSCH & LOMB (US) | 1997-06-25 | — | — | EP | disclosed |
| US-5512205-A | BIOMEDICAL ARTICLES, CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 1996-04-30 | — | — | US | disclosed |
| US-5310779-A | Compatible crosslinkers having vinyl-, acrylic-and/or styrenyl-groups to crosslink incompatible unsaturated addition monomers; contact lens; molding materials | BAUSCH & LOMB INCORPORATED (US) | 1994-05-10 | — | — | US | disclosed |
| CN-1074457-A | Novel crosslinking agent capable of being cured by ultraviolet rays for copolymerization | BAUSCH & LOMB (US) | 1993-07-21 | — | — | CN | disclosed |
| WO-1993009084-A1 | NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION | BAUSCH & LOMB INCORPORATED (US) | 1993-05-13 | — | — | WO | disclosed |