Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.31 |
| ▸ | PPARA | Q07869 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2783708 | 0.78 | CA2 (0.32) | — | |
| SCHEMBL7894378 | 0.78 | MAPT (0.40) | MAPTPOLBLMNAHSD17B10ESR1 | |
| SCHEMBL1882370 | 0.72 | ALDH1A1 (0.39) | MAPTLMNAALDH1A1HSD17B10ESR1 | |
| SCHEMBL16862414 | 0.72 | ALDH1A1 (0.42) | MAPTLMNAALDH1A1PPARG | |
| SCHEMBL121414 | 0.70 | ESR1 (0.42) | MAPTPOLBLMNAALDH1A1ESR1 | |
| SCHEMBL435743 | 0.68 | MAPT (0.36) | MAPTLMNAESR1ESR2NPSR1 | |
| SCHEMBL13621393 | 0.67 | ESR1 (0.34) | MAPTALDH1A1ESR1ESR2NPC1 | |
| SCHEMBL11809786 | 0.67 | LMNA (0.41) | MAPTPOLBLMNAALDH1A1ESR1 | |
| SCHEMBL11131500 | 0.67 | KMT2A (0.46) | MAPTPOLBLMNAALDH1A1L3MBTL1 | |
| SCHEMBL16603060 | 0.67 | ESR1 (0.41) | MAPTESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640221-B1 | SURFACE WETTABLE SILICONE HYDROGELS | BAUSCH & LOMB (US) | 1997-07-16 | — | — | EP | claimed |
| EP-0611367-B1 | NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION | BAUSCH & LOMB (US) | 1997-06-25 | — | — | EP | claimed |
| EP-0603268-B1 | WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS | BAUSCH & LOMB (US) | 1996-12-18 | — | — | EP | claimed |
| EP-0611380-B1 | WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE | BAUSCH & LOMB (US) | 1996-06-19 | — | — | EP | claimed |