Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420681 | 0.89 | HTT (0.44) | POLBHTTSMN1; SMN2LTB4RNR1H4 | |
| SCHEMBL8419007 | 0.88 | HTT (0.45) | POLBHTTSMN1; SMN2LTB4RNR1H4 | |
| SCHEMBL8768556 | 0.81 | ALDH1A1 (0.45) | POLBHPGDRAB9AALDH1A1CYP1A2 | |
| SCHEMBL8422577 | 0.81 | HTT (0.54) | POLBHTTSMN1; SMN2LTB4RNR1H4 | |
| SCHEMBL8768504 | 0.81 | ALDH1A1 (0.46) | POLBHTTSMN1; SMN2HPGDRAB9A | |
| SCHEMBL8422541 | 0.79 | POLB (0.48) | POLBHTTSMN1; SMN2LTB4RNR1H4 | |
| SCHEMBL8418610 | 0.79 | HTT (0.51) | POLBHTTSMN1; SMN2LTB4RNR1H4 | |
| SCHEMBL8420643 | 0.78 | POLB (0.51) | POLBHTTSMN1; SMN2LTB4RNR1H4 | |
| SCHEMBL8767951 | 0.78 | HTT (0.53) | POLBHTTSMN1; SMN2LTB4RNR1H4 | |
| SCHEMBL8767987 | 0.77 | HTT (0.49) | POLBHTTSMN1; SMN2LTB4RNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |