Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.49 |
| ▸ | PGK1 | P00558 | 1/20 | 0.48 |
| ▸ | PGK2 | P07205 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14665042 | 0.90 | ADORA2A (0.53) | ADORA2AADORA3ADORA1CYP1A2ADORA2B | |
| SCHEMBL14665046 | 0.90 | ADORA2A (0.53) | ADORA2AADORA3ADORA1CYP1A2ADORA2B | |
| SCHEMBL1066408 | 0.90 | ADORA2A (0.53) | ADORA2AADORA3ADORA1CYP1A2ADORA2B | |
| SCHEMBL30002378 | 0.90 | ADORA2A (0.52) | ADORA2AADORA3ADORA1CYP1A2ADORA2B | |
| SCHEMBL25496787 | 0.83 | ADORA2A (0.44) | ADORA2AADORA3ADORA1CYP1A2ADORA2B | |
| SCHEMBL18479661 | 0.78 | SLC29A1 (0.61) | ADORA2AADORA3ADORA1CYP1A2ADORA2B | |
| SCHEMBL27621467 | 0.77 | SLC29A1 (0.66) | ADORA2AADORA3ADORA1CYP1A2ADORA2B | |
| SCHEMBL30002219 | 0.76 | TYMP (0.56) | ADORA1 | |
| SCHEMBL8972045 | 0.76 | KDM4E (0.44) | ADORA3ADORA1 | |
| SCHEMBL26622653 | 0.76 | ACHE (0.52) | ADORA2AADORA3ADORA1SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592511-B1 | SEQUENCE-SPECIFIC BINDING POLYMERS FOR DUPLEX NUCLEIC ACIDS | ANTIVIRALS INC (US) | 1997-08-20 | — | — | EP | disclosed |
| US-5166315-A | Polynucleotides for genetic engineering | ANTI-GENE DEVELOPMENT GROUP (US) | 1992-11-24 | — | — | US | disclosed |