Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23723572 | 0.80 | ALDH1A1 (0.45) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL2075524 | 0.73 | ALDH1A1 (0.38) | HPGDRAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL6558533 | 0.73 | CYP2A6 (0.35) | HPGDRAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL9956507 | 0.71 | CES2 (0.38) | HPGDKMT2AMEN1ALDH1A1TRPA1 | |
| SCHEMBL3700594 | 0.71 | TSHR (0.39) | HPGDKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL15880060 | 0.71 | NOTUM (0.47) | HPGDKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL15878889 | 0.71 | ALDH1A1 (0.50) | HPGDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5078453 | 0.70 | LTA4H (0.48) | KMT2ACYP1A2ALOX15TDP1POLB | |
| Hydrochloric Acid SCHEMBL28200481 | 0.70 | TSHR (0.38) | HPGDKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL8794645 | 0.68 | TSHR (0.48) | HPGDNPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592511-B1 | SEQUENCE-SPECIFIC BINDING POLYMERS FOR DUPLEX NUCLEIC ACIDS | ANTIVIRALS INC (US) | 1997-08-20 | — | — | EP | disclosed |
| EP-0592511-A1 | SEQUENCE-SPECIFIC BINDING POLYMERS FOR DUPLEX NUCLEIC ACIDS. | ANTIVIRALS INC (US) | 1994-04-20 | — | — | EP | disclosed |
| WO-1993000352-A1 | SEQUENCE-SPECIFIC BINDING POLYMERS FOR DUPLEX NUCLEIC ACIDS | ANTIVIRALS INC. (US) | 1993-01-07 | — | — | WO | disclosed |
| US-5166315-A | Polynucleotides for genetic engineering | ANTI-GENE DEVELOPMENT GROUP (US) | 1992-11-24 | — | — | US | disclosed |