Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.49 |
| ▸ | CCR5 | P51681 | 8/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31550560 | 0.82 | SIGMAR1 (0.59) | SIGMAR1FKBP1ATMEM97 | |
| SCHEMBL13684267 | 0.79 | L3MBTL1 (0.63) | SIGMAR1CCR5 | |
| SCHEMBL784814 | 0.77 | CCR5 (0.60) | CCR5 | |
| SCHEMBL13434086 | 0.77 | CCR5 (0.59) | SIGMAR1CCR5 | |
| SCHEMBL25184408 | 0.77 | SIGMAR1 (0.56) | SIGMAR1FKBP1A | |
| SCHEMBL25416510 | 0.77 | SIGMAR1 (0.56) | SIGMAR1FKBP1A | |
| SCHEMBL1240952 | 0.76 | SIGMAR1 (0.50) | SIGMAR1FKBP1ATMEM97 | |
| SCHEMBL3786414 | 0.74 | FKBP1A (0.73) | FKBP1A | |
| SCHEMBL28811887 | 0.74 | FKBP1A (0.73) | FKBP1A | |
| SCHEMBL25184580 | 0.73 | SIGMAR1 (0.51) | SIGMAR1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619178-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | disclosed |