Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6893946 | 0.79 | AR (0.40) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL70068 | 0.79 | ALDH1A1 (0.48) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL30027143 | 0.79 | ALDH1A1 (0.48) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL27963029 | 0.79 | ALDH1A1 (0.48) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL10413349 | 0.73 | CYP3A4 (0.33) | — | |
| Phosphoric Acid SCHEMBL27960768 | 0.73 | ALDH1A1 (0.39) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL5694506 | 0.72 | ALDH1A1 (0.42) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| Hydroquinone SCHEMBL28076397 | 0.72 | LMNA (0.55) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL8768201 | 0.72 | CA2 (0.39) | ALDH1A1ALOX15HSD17B10TDP1NR1I2 | |
| SCHEMBL27878128 | 0.71 | ALDH1A1 (0.37) | ALDH1A1ALOX15HSD17B10TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1983004258-A1 | ACYLATED HINDERED HEXAHYDROPYRIMIDINES AND THEIR USE AS LIGHT STABILIZING AGENTS | FERRO CORPORATION (US) | 1983-12-08 | — | — | WO | claimed |
| US-4404302-A | FOR POLYMERS | FERRO CORPORATION (US) | 1983-09-13 | — | — | US | claimed |
| EP-0652894-B1 | SYNTHETIC PEPTIDE LUNG SURFACTANTS HAVING COVALENTLY BONDED ANTIOXIDANTS | MERRELL PHARMA INC (US) | 1997-09-03 | — | — | EP | disclosed |