Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.45 |
| ▸ | ITGAV | P06756 | 1/20 | 0.45 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31448014 | 0.83 | KEAP1 (0.62) | KEAP1KDM4ERAB9AEGLN1MAPT | |
| SCHEMBL17087190 | 0.83 | KEAP1 (0.51) | HPGDALDH1A1HSD17B10KEAP1KDM4E | |
| SCHEMBL27419805 | 0.81 | BACE1 (0.50) | ALDH1A1KEAP1KDM4EEGLN1ITGB3 | |
| SCHEMBL21800978 | 0.80 | CYP2C19 (0.58) | HPGDALDH1A1KEAP1KDM4ERAB9A | |
| SCHEMBL13992226 | 0.80 | BACE1 (0.68) | HPGDPPARGBACE1MAPT | |
| SCHEMBL30289977 | 0.78 | KMT2A (0.65) | HPGDALDH1A1HSD17B10KEAP1KDM4E | |
| SCHEMBL27450922 | 0.78 | KEAP1 (0.66) | ALDH1A1KEAP1KDM4ERAB9AEGLN1 | |
| SCHEMBL4952951 | 0.78 | LMNA (0.63) | HPGDALDH1A1HSD17B10KDM4ERAB9A | |
| SCHEMBL7345812 | 0.78 | BACE1 (0.47) | ALDH1A1KEAP1KDM4EEGLN1ITGB3 | |
| SCHEMBL1649572 | 0.77 | CHRNB2 (0.68) | ALDH1A1KEAP1EGLN1PPARGKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792146-A1 | INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES | HEMASURE, INC. (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1997002028-A1 | INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES | HEMASURE, INC. (US) | 1997-01-23 | — | — | WO | disclosed |