Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15756849 | 0.76 | ACP1 (0.48) | LMNAADORA2BHTT | |
| SCHEMBL10888835 | 0.71 | LMNA (1.00) | LMNAADORA2BALDH1A1KDM4ETDP1 | |
| SCHEMBL4560485 | 0.68 | CSNK2A2 (0.55) | LMNACSNK2A2CSNK2A1ADORA2BALDH1A1 | |
| SCHEMBL18704122 | 0.67 | ADORA2B (0.52) | LMNACSNK2A2CSNK2A1ADORA2BHDAC6 | |
| Hydrochloric Acid SCHEMBL18742217 | 0.66 | ADORA2B (0.51) | LMNACSNK2A2CSNK2A1ADORA2BHDAC6 | |
| SCHEMBL18742219 | 0.63 | LMNA (0.51) | LMNACSNK2A2CSNK2A1ADORA2BALDH1A1 | |
| SCHEMBL15493532 | 0.62 | CSNK2A1 (1.00) | LMNACSNK2A2CSNK2A1ADORA2BALDH1A1 | |
| SCHEMBL29965130 | 0.62 | CSNK2A2 (0.51) | LMNACSNK2A2CSNK2A1ADORA2BALDH1A1 | |
| Hydrochloric Acid SCHEMBL18742227 | 0.62 | LMNA (0.50) | LMNACSNK2A2CSNK2A1ADORA2BALDH1A1 | |
| SCHEMBL4735463 | 0.62 | CDK1 (0.49) | LMNACSNK2A2CSNK2A1ADORA2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792283-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996015143-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1996-05-23 | — | — | WO | disclosed |