SCHEMBL28340407

SCHEMBL28340407

CC(SC(=O)C(=O)O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.41
SRC P12931 1/20 0.41
LMNA P02545 2/20 0.40
MAPK1 P28482 1/20 0.40
ALOX5 P09917 1/20 0.40
KMT2A Q03164 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
RECQL P46063 1/20 0.39
MAPT P10636 1/20 0.39
PTGS2 P35354 1/20 0.38
DAO P14920 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10076865 0.86 HPGD (0.44) CYP2D6SRCLMNAMAPK1ALOX5
SCHEMBL1959777 0.81 TSHR (0.46) CYP2D6SRCLMNAMAPK1ALOX5
SCHEMBL27838181 0.78 GPR139 (0.49) CYP2D6SRCLMNAMAPK1KMT2A
SCHEMBL9817188 0.75 CYP2C19 (0.41) CYP2D6SRCLMNAMAPK1ALOX5
SCHEMBL11443376 0.74 ADRA2C (0.40) CYP2D6LMNAKMT2ADAOHSD17B10
SCHEMBL6535241 0.74 ADRA2C (0.40) CYP2D6LMNAKMT2ADAOHSD17B10
SCHEMBL3929030 0.73 POLB (0.44) LMNAKMT2ACES2CES1MAPT
SCHEMBL8768543 0.73 HCAR2 (0.51) CYP2D6ALOX5KMT2AHSD17B10
SCHEMBL12590975 0.72 ADRA2C (0.39) CYP2D6LMNAKMT2ADAOHSD17B10
SCHEMBL14355125 0.72 ADRA2C (0.39) CYP2D6LMNAKMT2ADAOHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110590626-A Process for preparing oxomercaptoacetic acids 中国科学技术大学 2019-12-20 CN disclosed