Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4771370 | 0.82 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1POLBGAAKMT2A | |
| SCHEMBL4618373 | 0.79 | KDM4E (0.46) | SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL4467734 | 0.78 | TSHR (0.43) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL4767676 | 0.77 | B3GNT2 (0.43) | SMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL6243233 | 0.76 | KMT2A (0.55) | SMN1; SMN2ALDH1A1POLBKMT2A | |
| SCHEMBL1702032 | 0.76 | TSHR (0.55) | ALDH1A1GAAKMT2A | |
| SCHEMBL126983 | 0.76 | KMT2A (0.44) | SMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL14592881 | 0.74 | DAO (0.41) | SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL7832602 | 0.74 | ADRA1D (0.42) | SMN1; SMN2 | |
| SCHEMBL7403411 | 0.73 | ALOX15 (0.45) | SMN1; SMN2ALDH1A1POLBGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792146-A1 | INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES | HEMASURE, INC. (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1997002028-A1 | INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES | HEMASURE, INC. (US) | 1997-01-23 | — | — | WO | disclosed |