Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768931 | 0.88 | PPARA (0.52) | TSHRHTTGAAALDH1A1PPARA | |
| SCHEMBL8768915 | 0.87 | TSHR (0.42) | TSHRHTTGAALMNAALDH1A1 | |
| SCHEMBL8768099 | 0.87 | TSHR (0.52) | TSHRHTTGAALMNAALDH1A1 | |
| SCHEMBL8768980 | 0.84 | PPARA (0.50) | TSHRHTTGAALMNAALDH1A1 | |
| SCHEMBL8926594 | 0.83 | PPARA (0.52) | TSHRHTTGAAPPARAABCB11 | |
| SCHEMBL8768806 | 0.82 | PPARA (0.50) | TSHRHTTGAALMNAALDH1A1 | |
| SCHEMBL8925577 | 0.79 | PPARA (0.60) | TSHRHTTGAALMNAPPARA | |
| SCHEMBL8924339 | 0.76 | GAA (0.52) | TSHRHTTGAALMNAALDH1A1 | |
| SCHEMBL8924220 | 0.75 | TAS1R3 (0.54) | TSHRHTTGAAALDH1A1PPARA | |
| SCHEMBL8925832 | 0.75 | PPARA (0.43) | TSHRHTTGAALMNAPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658944-A | ANTICHOLESTEROL AGENTS | THE UNIVERSITY OF SOUTH CAROLINA (US) | 1997-08-19 | — | — | US | disclosed |