SCHEMBL8769102

SCHEMBL8769102

CCCCC1(CC)CSc2cc(OC)c(OC)cc2N(c2ccccc2)C1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
NPSR1 Q6W5P4 2/20 0.36
GPR55 Q9Y2T6 2/20 0.36
LMNA P02545 2/20 0.35
KDM4E B2RXH2 1/20 0.35
DRD2 P14416 5/20 0.34
DRD3 P35462 4/20 0.34
PDE4A P27815 1/20 0.34
PDE4B Q07343 1/20 0.34
PDE4C Q08493 1/20 0.34
PDE4D Q08499 1/20 0.34
SLC10A2 Q12908 4/20 0.34
HTR1A P08908 2/20 0.33
ELANE P08246 1/20 0.33
USP2 O75604 1/20 0.32
POLB P06746 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ADRA2A P08913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21589578 0.93 SLC10A2 (0.36) ALDH1A1NPSR1GPR55LMNAKDM4E
SCHEMBL21585981 0.92 DRD2 (0.32) ALDH1A1NPSR1GPR55LMNAKDM4E
SCHEMBL30912777 0.92 DRD2 (0.32) ALDH1A1NPSR1GPR55LMNAKDM4E
SCHEMBL8768253 0.92 DRD2 (0.32) ALDH1A1NPSR1GPR55LMNAKDM4E
SCHEMBL8769228 0.92 GAA (0.34) ALDH1A1NPSR1GPR55LMNAKDM4E
SCHEMBL21586027 0.92 DRD2 (0.32) ALDH1A1NPSR1GPR55LMNAKDM4E
SCHEMBL21585970 0.92 DRD2 (0.32) ALDH1A1NPSR1GPR55LMNAKDM4E
SCHEMBL21586102 0.90 OPRM1 (0.32) ALDH1A1NPSR1GPR55LMNAKDM4E
SCHEMBL21589646 0.90 DRD2 (0.31) ALDH1A1NPSR1GPR55LMNAKDM4E
SCHEMBL26986255 0.90 FGFR1 (0.36) ALDH1A1NPSR1GPR55LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0792268-A1 HYPOLIPIDEMIC BENZOTHIAZEPINES THE WELLCOME FOUNDATION LIMITED (GB) 1997-09-03 EP claimed
WO-1996016051-A1 HYPOLIPIDEMIC BENZOTHIAZEPINES THE WELLCOME FOUNDATION LIMITED (GB) 1996-05-30 WO claimed