Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 13/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11060036 | 0.84 | CD274 (0.45) | CD274PDCD1FFAR1FFAR4 | |
| SCHEMBL11060029 | 0.84 | CD274 (0.45) | CD274PDCD1FFAR1FFAR4 | |
| SCHEMBL8769841 | 0.79 | CD274 (0.43) | CD274PDCD1 | |
| SCHEMBL8769173 | 0.78 | CD274 (0.48) | CD274PDCD1 | |
| SCHEMBL8769176 | 0.78 | CD274 (0.51) | CD274PDCD1 | |
| SCHEMBL11057216 | 0.71 | CD274 (0.40) | CD274PDCD1 | |
| SCHEMBL11057211 | 0.71 | CD274 (0.40) | CD274PDCD1 | |
| SCHEMBL30531243 | 0.70 | FFAR1 (0.42) | CD274PDCD1FFAR1FFAR4TRPV1 | |
| SCHEMBL21620376 | 0.69 | CD274 (0.53) | CD274PDCD1 | |
| SCHEMBL11048772 | 0.69 | CD274 (0.39) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792870-A1 | Process for the preparation of ketoximethers by coupling with boronic acid derivatives | Hoechst Schering AgrEvo GmbH (DE) | 1997-09-03 | — | — | EP | disclosed |