SCHEMBL8769319

SCHEMBL8769319

CCCCCCc1ccc(-c2ncc(-c3ccc(OC)cc3)s2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 1/20 0.59
SENP8 Q96LD8 1/20 0.59
SENP7 Q9BQF6 1/20 0.59
SENP6 Q9GZR1 1/20 0.59
RAB9A P51151 5/20 0.46
MAPT P10636 4/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 2/20 0.46
MEN1 O00255 2/20 0.46
USP2 O75604 2/20 0.46
KMT2A Q03164 2/20 0.46
GAA P10253 1/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MMP2 P08253 3/20 0.45
MMP9 P14780 3/20 0.45
NPBWR1 P48145 1/20 0.44
CCNB2 O95067 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8768346 1.00 CASP3 (0.59) CASP3SENP8SENP7SENP6RAB9A
SCHEMBL8883086 0.91 RAB9A (0.54) CASP3SENP8SENP7SENP6RAB9A
SCHEMBL7933637 0.91 RAB9A (0.54) CASP3SENP8SENP7SENP6RAB9A
SCHEMBL8884758 0.90 RAB9A (0.51) CASP3SENP8SENP7SENP6RAB9A
SCHEMBL8769198 0.90 RAB9A (0.51) CASP3SENP8SENP7SENP6RAB9A
SCHEMBL8415817 0.87 RAB9A (0.50) CASP3SENP8SENP7SENP6RAB9A
SCHEMBL8547071 0.85 LTA4H (0.48) RAB9AMAPTL3MBTL1SMN1; SMN2ALDH1A1
SCHEMBL8883338 0.84 THRB (0.51) CASP3SENP8SENP7SENP6RAB9A
SCHEMBL8984250 0.84 RAB9A (0.49) CASP3SENP8SENP7SENP6RAB9A
SCHEMBL8769157 0.84 KDM4E (0.59) RAB9AMAPTSMN1; SMN2ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0460624-B1 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1997-09-10 EP disclosed
US-5595685-A THIAZOLE DERIVATIVE CANON KABUSHIKI KAISHA (JP) 1997-01-21 US disclosed
EP-0476567-B1 Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1996-06-12 EP disclosed
EP-0500072-B1 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1995-05-03 EP disclosed
EP-0499222-B1 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1995-05-03 EP disclosed
EP-0439170-B1 Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus CANON KK (JP) 1995-04-19 EP disclosed
US-5269964-A Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1993-12-14 US disclosed
US-5262083-A Oxazole or thiazole compounds CANON KABUSHIKI KAISHA (JP) 1993-11-16 US disclosed
US-5250218-A Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1993-10-05 US disclosed
US-5217645-A Low temperature, high speed response CANON KABUSHIKI KAISHA (JP) 1993-06-08 US disclosed
EP-0500072-A1 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1992-08-26 EP disclosed
EP-0499222-A1 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1992-08-19 EP disclosed
EP-0476567-A1 Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1992-03-25 EP disclosed
EP-0460624-A2 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1991-12-11 EP disclosed
EP-0439170-A2 Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus CANON KABUSHIKI KAISHA (JP) 1991-07-31 EP disclosed