Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | GRK6 | P43250 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769707 | 0.83 | ERN1 (0.43) | DGAT1ERN1KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL29053308 | 0.76 | KDM4E (0.40) | DGAT1KEAP1NFE2L2ALDH1A1KDM4E | |
| SCHEMBL8769009 | 0.76 | DGAT1 (0.45) | DGAT1ERN1KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL5713285 | 0.73 | KEAP1 (0.50) | DGAT1ERN1KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL9389804 | 0.71 | DGAT1 (0.50) | DGAT1ERN1KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL30102606 | 0.70 | TDP1 (0.42) | MAPTEIF2AK2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL656173 | 0.70 | TDP1 (0.42) | MAPTEIF2AK2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL41435 | 0.69 | KEAP1 (0.64) | KEAP1NFE2L2ALDH1A1KDM4EGAA | |
| SCHEMBL7950797 | 0.68 | AKR1B1 (0.43) | DGAT1ERN1ALDH1A1KDM4EKMT2A | |
| SCHEMBL31070426 | 0.68 | TDP1 (0.40) | EIF2AK2CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0568839-B1 | Flame-retardant resin composition, electric wire using same, and tube made of same | SUMITOMO ELECTRIC INDUSTRIES (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5650205-A | WIRE COATED WITH THERMOPLASTIC RESIN CONTAINING ANTIMONY TRIOXIDE AND A BIS(HALOPHENYL)-TEREPHTHALAMIDE; HEAT AND BLOOM RESISTANCE | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1997-07-22 | — | — | US | disclosed |
| EP-0568839-A1 | Flame-retardant resin composition, electric wire using same, and tube made of same | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1993-11-10 | — | — | EP | disclosed |