Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 6/20 | 1.00 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 1.00 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 1.00 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 1.00 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 1.00 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 1.00 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.95 |
| ▸ | RAD52 | P43351 | 3/20 | 1.00 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 2/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 2/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 2/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | EGFR | P00533 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | PLA2G1B | P04054 | 1/20 | 1.00 |
| ▸ | ERBB2 | P04626 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1331692 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL557155 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL5286954 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL1547466 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL5085309 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL8650670 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL4540499 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL1331186 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Cetylpyridinium SCHEMBL151799 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL177665 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600659-B1 | Toner and developer compositions with pyridinium compounds and tetrasubstituted ammonium salts as charge enhancing additives | XEROX CORP (US) | 1997-07-30 | — | — | EP | claimed |
| EP-0600659-A1 | Toner and developer compositions with pyridinium compounds and tetrasubstituted ammonium salts as charge enhancing additives | XEROX CORPORATION (US) | 1994-06-08 | — | — | EP | claimed |
| US-5304449-A | Toner and developer compositions with pyridinium compounds and tetrasubstituted ammonium salts as charge enhancing additives | XEROX CORPORATION (US) | 1994-04-19 | — | — | US | claimed |
| EP-0600659-B1 | Toner and developer compositions with pyridinium compounds and tetrasubstituted ammonium salts as charge enhancing additives | XEROX CORP (US) | 1997-07-30 | — | — | EP | disclosed |
| EP-0600659-A1 | Toner and developer compositions with pyridinium compounds and tetrasubstituted ammonium salts as charge enhancing additives | XEROX CORPORATION (US) | 1994-06-08 | — | — | EP | disclosed |
| US-5304449-A | Toner and developer compositions with pyridinium compounds and tetrasubstituted ammonium salts as charge enhancing additives | XEROX CORPORATION (US) | 1994-04-19 | — | — | US | disclosed |
| US-4792513-A | Positively charged toner compositions | XEROX CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |
| US-4604338-A | RESIN PARTICLES, COLORED PIGMENTS AND CHARGE ENHANCING ADDITIVE CONSISTING OF ALKYLPYRIDINIUM HALIDE, ORGANIC SULFONATES OR SULFATES | XEROX CORPORATION (US) | 1986-08-05 | — | — | US | disclosed |
| US-4460672-A | Positively charged electrostatic toner contains low molecular weight waxy material and pyridinium halide or organic sulfonate | XEROX CORPORATION (US) | 1984-07-17 | — | — | US | disclosed |
| EP-0022347-B1 | ELECTROSTATOGRAPHIC DEVELOPER MIXTURE | XEROX CORPORATION (US) | 1984-02-01 | — | — | EP | disclosed |
| EP-0005952-B1 | ELECTROSTATOGRAPHIC TONER CONTAINING AN ALKYL PYRIDINIUM COMPOUND AND IMAGING METHOD | XEROX CORPORATION (US) | 1983-12-28 | — | — | EP | disclosed |
| US-4324851-A | COMPRISING A RESIN, COLORED PIGMENTS, AND ALKYL PYRIDINIUM COMPOUNDS | XEROX CORPORATION (US) | 1982-04-13 | — | — | US | disclosed |
| US-4304830-A | HIGH-SPEED CHARGING WHEN ADDING A PYRIDINIUM HALIDE OR A HYDRATE TO A CHARGED DEVELOPER | XEROX CORPORATION (US) | 1981-12-08 | — | — | US | disclosed |
| US-4299903-A | BUTYL METHACRYLATE-STYRENE OR BUTADIENE-STYRENE COPOLYMER MODIFIED WITH A QUATERNARY AMMONIUM COMPOUND | XEROX CORPORATION (US) | 1981-11-10 | — | — | US | disclosed |
| US-4298672-A | ELECTROGRAPHY | XEROX CORPORATION (US) | 1981-11-03 | — | — | US | disclosed |
| US-4291112-A | QUATERNARY AMMONIUM COMPOUND, AMINE, PYRIDINIUM COMPOUND, OR IMIDAZOLINE COMPOUND | XEROX CORPORATION (US) | 1981-09-22 | — | — | US | disclosed |
| US-4264697-A | TONER RESIN, COLORANT, AND A CHARGE INDUCTING HYDRAZINIUM OR PYRIDINIUM COMPOUND | XEROX CORPORATION (US) | 1981-04-28 | — | — | US | disclosed |
| EP-0022347-A1 | Electrostatographic developer mixture | XEROX CORPORATION (US) | 1981-01-14 | — | — | EP | disclosed |
| EP-0005952-A1 | Electrostatographic toner containing an alkyl pyridinium compound and imaging method | XEROX CORPORATION (US) | 1979-12-12 | — | — | EP | disclosed |