Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 6/20 | 1.00 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 1.00 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 1.00 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 1.00 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 1.00 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 1.00 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.95 |
| ▸ | RAD52 | P43351 | 3/20 | 1.00 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 2/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 2/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 2/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | EGFR | P00533 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | PLA2G1B | P04054 | 1/20 | 1.00 |
| ▸ | ERBB2 | P04626 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8770083 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL1331692 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL557155 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL5286954 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL1547466 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL5085309 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL8650670 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL4540499 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL1331186 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Cetylpyridinium SCHEMBL151799 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 757 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140476-A1 | RESIN PERMEABLE CERAMIC WITH ANTIBACTERIAL FUNCTION AND PREPARATION METHOD THEREFOR | 爱迪特（秦皇岛）科技股份有限公司 | 2024-07-04 | — | — | WO | claimed |
| CN-117753387-A | Covalent organic framework nanocapsule material and emulsion acceleration polymerization method thereof | 浙江大学 | 2024-03-26 | — | — | CN | claimed |
| WO-2023061256-A1 | SILICON-ALUMINUM MOLECULAR SIEVE SCM-36, MANUFACTURING METHOD THEREFOR AND APPLICATION THEREOF | 中国石油化工股份有限公司 | 2023-04-20 | — | — | WO | claimed |
| CN-115959681-A | SCM-36 molecular sieves, methods of making, and uses thereof | 中国石油化工股份有限公司 | 2023-04-14 | — | — | CN | claimed |
| US-11549134-B2 | Modified amadoriase and method for producing the same, agent for improving surfactant resistance of amadoriase and composition for measuring HbA1c using the same | KIKKOMAN CORPORATION (JP) | 2023-01-10 | — | — | US | claimed |
| CN-113383775-A | Compound quaternary ammonium salt low-temperature disinfectant and preparation method thereof | 广东环凯生物技术有限公司 | 2021-09-14 | — | — | CN | claimed |
| US-20200263228-A1 | MODIFIED AMADORIASE AND METHOD FOR PRODUCING THE SAME, AGENT FOR IMPROVING SURFACTANT RESISTANCE OF AMADORIASE AND COMPOSITION FOR MEASURING HbA1c USING THE SAME | KIKKOMAN CORPORATION (JP) | 2020-08-20 | — | — | US | claimed |
| CN-111441054-A | High-acid high-salt corrosion inhibitor suitable for low-temperature part of oil refining device | 丁双龙 | 2020-07-24 | — | — | CN | claimed |
| CN-107155433-B | Application of surfactant in soil salinization reduction and method | 昆明理工大学 | 2020-04-07 | — | — | CN | claimed |
| CN-107556579-A | A kind of antistatic filling master batch of polyethylene and preparation method thereof | 贵州通汇塑料科技有限公司 | 2018-01-09 | — | — | CN | claimed |
| US-20050107273-A1 | Bar soap composition with reduced bar wear properties | COLGATE-PALMOTIVE COMPANY | 2005-05-19 | — | — | US | claimed |
| WO-2005044970-A1 | BAR SOAP COMPOSITION WITH REDUCED BAR WEAR PROPERTIES | COLGATE-PALMOLIVE COMPANY (US) | 2005-05-19 | — | — | WO | claimed |
| US-6838420-B2 | A translucent or transparent composition comprising about 3 to about 40 wt. % soap, about 4 to about 40 wt. % of at least one synthetic surfactant, and water, lower monohydric alcohol, a humectant, a structurant, and gellant are not 0 at the | COLGATE-PALMOLIVE COMPANY (US) | 2005-01-04 | — | — | US | claimed |
| EP-0805672-B1 | METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH | HOMOLA ANDREW M (US) | 2004-08-25 | — | — | EP | claimed |
| US-5367876-A | Apparatus for controlling of automotive exhaust emissions by treatment of exhausting gases traveling through an automotive exhaust conduit | HARPER III RAYMOND F (US) | 1994-11-29 | — | — | US | claimed |
| US-5344738-A | Process of making toner compositions | XEROX CORPORATION (US) | 1994-09-06 | — | — | US | claimed |
| EP-0233247-A4 | METHOD FOR WASTEWATER TREATMENT. | US ENVIRONMENT RESOURCES (US) | 1988-12-12 | — | — | EP | claimed |
| EP-0233247-A1 | METHOD FOR WASTEWATER TREATMENT | UNITED STATES ENVIRONMENTAL RESOURCES CORPORATION (US) | 1987-08-26 | — | — | EP | claimed |
| WO-1987000516-A1 | METHOD FOR WASTEWATER TREATMENT | UNITED STATES ENVIRONMENTAL RESOURCES CORPORATION (US) | 1987-01-29 | — | — | WO | claimed |
| US-4615807-A | QUATERNARY AMMONIUM SALTS AND ORGANOTIN MIXTURE TO DISINFECT | UNITED STATES ENVIRONMENTAL RESOURCES, CORP. (US) | 1986-10-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107273-A1 | Bar soap composition with reduced bar wear properties | DDHD2, SORD, CRABP2 | ACHE 1725/4885CHRM2 4045/4885CHRM1 4250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.