Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 6/20 | 1.00 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 1.00 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 1.00 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 1.00 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 1.00 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 1.00 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.95 |
| ▸ | RAD52 | P43351 | 3/20 | 1.00 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 2/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 2/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 2/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | EGFR | P00533 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | PLA2G1B | P04054 | 1/20 | 1.00 |
| ▸ | ERBB2 | P04626 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8770083 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL1331692 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL557155 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL5286954 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL1547466 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL5085309 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL8650670 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL4540499 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Cetylpyridinium SCHEMBL151799 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL177665 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11549134-B2 | Modified amadoriase and method for producing the same, agent for improving surfactant resistance of amadoriase and composition for measuring HbA1c using the same | KIKKOMAN CORPORATION (JP) | 2023-01-10 | — | — | US | claimed |
| WO-2020243345-A1 | MONODISPERSED NANOCARBONS PREPARED FROM POLYSULFONATED NANOPOLYMERS | SIGMA-ALDRICH CO. LLC (US) | 2020-12-03 | — | — | WO | claimed |
| US-20200263228-A1 | MODIFIED AMADORIASE AND METHOD FOR PRODUCING THE SAME, AGENT FOR IMPROVING SURFACTANT RESISTANCE OF AMADORIASE AND COMPOSITION FOR MEASURING HbA1c USING THE SAME | KIKKOMAN CORPORATION (JP) | 2020-08-20 | — | — | US | claimed |
| US-20160186232-A1 | MODIFIED AMADORIASE AND METHOD FOR PRODUCING THE SAME, AGENT FOR IMPROVING SURFACTANT RESISTANCE OF AMADORIASE AND COMPOSITION FOR MEASURING HbA1c USING THE SAME | KIKKOMAN CORPORATION (JP) | 2016-06-30 | — | — | US | claimed |
| EP-3031914-A1 | MODIFIED AMADORIASE AND METHOD FOR PRODUCING SAME, AGENT FOR IMPROVING SURFACTANT-RESISTANCE OF AMADORIASE AND COMPOSITION FOR MEASURING HbA1c USING SAME | Kikkoman Corporation (JP) | 2016-06-15 | — | — | EP | claimed |
| US-20070004857-A1 | CARBON NANOTUBE-FILLED COMPOSITES PREPARED BY IN-SITU POLYMERIZATION | BOARD OF THE REGENTS OF THE UNIVERSITY OF OKLAHOMA, THE | 2007-01-04 | — | — | US | claimed |
| US-7153903-B1 | Carbon nanotube-filled composites prepared by in-situ polymerization | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2006-12-26 | — | — | US | claimed |
| EP-1534774-A4 | CARBON NANOTUBE-FILLED COMPOSITES | UNIV OKLAHOMA (US) | 2006-07-26 | — | — | EP | claimed |
| EP-1534774-A2 | CARBON NANOTUBE-FILLED COMPOSITES | The Board of Regents of The University of Oklahoma (US) | 2005-06-01 | — | — | EP | claimed |
| US-20040010066-A1 | Flame retardant dispersible powders on a wax, polymer, or organic carrier | DEVINE STEPHEN J (GB) | 2004-01-15 | — | — | US | claimed |
| WO-2004001107-A2 | CARBON NANOTUBE-FILLED COMPOSITES | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2003-12-31 | — | — | WO | claimed |
| EP-1297056-A1 | FLAME RETARDANT DISPERSIBLE POWDERS ON A WAX, POLYMER, OR ORGANIC CARRIER | Pabu Services, Inc. (US) | 2003-04-02 | — | — | EP | claimed |
| WO-2002002675-A1 | FLAME RETARDANT DISPERSIBLE POWDERS ON A WAX, POLYMER, OR ORGANIC CARRIER | PABU SERVICES, INC. (US) | 2002-01-10 | — | — | WO | claimed |
| US-20260022311-A1 | SEMICONDUCTOR SUBSTRATE CLEANING COMPOSITION, AND METHOD FOR PRODUCING SEMICONDUCTOR SUBSTRATE USING SAME | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2026-01-22 | — | — | US | disclosed |
| CN-120129771-A | Aqueous composition for etching, etching method using same, and method for manufacturing semiconductor substrate | 三菱瓦斯化学株式会社 | 2025-06-10 | — | — | CN | disclosed |
| EP-4564403-A1 | SEMICONDUCTOR SUBSTRATE CLEANING COMPOSITION, AND METHOD FOR PRODUCING SEMICONDUCTOR SUBSTRATE USING SAME | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2025-06-04 | — | — | EP | disclosed |
| US-4423088-A | USING COUPLING AGENT WITH CHARGE OPPOSITE TO CHARGE ON ASPHALT EMULSION | CHEVRON RESEARCH COMPANY (US) | 1983-12-27 | — | — | US | disclosed |
| EP-0091453-A1 | PROCESS FOR THE PREPARATION OF POLYMER PARTICLES. | SINTEF (NO) | 1983-10-19 | — | — | EP | disclosed |
| WO-1983001453-A1 | PROCESS FOR PREPARING AN AQUEOUS DISPERSION OF ORGANIC MATERIAL AND OPTIONALLY FURTHER CONVERSION TO A POLYMER DISPERSION | UGELSTAD, JOHN | 1983-04-28 | — | — | WO | disclosed |
| US-4252656-A | AEROSOL CONTAINING CATIONIC POLYMER, SOFTENING AND FOAMING AGENTS, STABILIZER, HUMECTANT, WATER, AND PROPELLANT; LAUNDRY DRIERS | COLGATE-PALMOLIVE COMPANY (US) | 1981-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260022311-A1 | SEMICONDUCTOR SUBSTRATE CLEANING COMPOSITION, AND METHOD FOR PRODUCING SEMICONDUCTOR SUBSTRATE USING SAME | SFN, SEM1, VAV1 | ACHE 1452/4885CHRM2 1982/4885CHRM1 1757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.