Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 6/20 | 1.00 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 1.00 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 1.00 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 1.00 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 1.00 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 1.00 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.95 |
| ▸ | RAD52 | P43351 | 3/20 | 1.00 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 2/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 2/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 2/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | EGFR | P00533 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | PLA2G1B | P04054 | 1/20 | 1.00 |
| ▸ | ERBB2 | P04626 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8770083 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL557155 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL5286954 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL1547466 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL5085309 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL8650670 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL4540499 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL1331186 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Cetylpyridinium SCHEMBL151799 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL177665 | 1.00 | ACHE (1.00) | ACHERAD52HSP90AA1CHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11549134-B2 | Modified amadoriase and method for producing the same, agent for improving surfactant resistance of amadoriase and composition for measuring HbA1c using the same | KIKKOMAN CORPORATION (JP) | 2023-01-10 | — | — | US | claimed |
| US-20200263228-A1 | MODIFIED AMADORIASE AND METHOD FOR PRODUCING THE SAME, AGENT FOR IMPROVING SURFACTANT RESISTANCE OF AMADORIASE AND COMPOSITION FOR MEASURING HbA1c USING THE SAME | KIKKOMAN CORPORATION (JP) | 2020-08-20 | — | — | US | claimed |
| US-20160186232-A1 | MODIFIED AMADORIASE AND METHOD FOR PRODUCING THE SAME, AGENT FOR IMPROVING SURFACTANT RESISTANCE OF AMADORIASE AND COMPOSITION FOR MEASURING HbA1c USING THE SAME | KIKKOMAN CORPORATION (JP) | 2016-06-30 | — | — | US | claimed |
| EP-3031914-A1 | MODIFIED AMADORIASE AND METHOD FOR PRODUCING SAME, AGENT FOR IMPROVING SURFACTANT-RESISTANCE OF AMADORIASE AND COMPOSITION FOR MEASURING HbA1c USING SAME | Kikkoman Corporation (JP) | 2016-06-15 | — | — | EP | claimed |
| CN-105473715-A | Modified amadoriase and method for producing same, surfactant resistance improver for amadoriase, and composition for measurement of HbA1c using same | KIKKOMAN CORP | 2016-04-06 | — | — | CN | claimed |
| CN-111398605-B | Glycosylated hemoglobin measurement composition | 龟甲万株式会社 | 2024-04-05 | — | — | CN | disclosed |
| EP-3279323-B1 | AMADORIASE HAVING IMPROVED SPECIFIC ACTIVITY | KIKKOMAN CORP (JP) | 2023-03-08 | — | — | EP | disclosed |
| US-11549134-B2 | Modified amadoriase and method for producing the same, agent for improving surfactant resistance of amadoriase and composition for measuring HbA1c using the same | KIKKOMAN CORPORATION (JP) | 2023-01-10 | — | — | US | disclosed |
| US-10934530-B2 | Amadoriase having improved specific activity | KIKKOMAN CORPORATION (JP) | 2021-03-02 | — | — | US | disclosed |
| EP-3760717-A1 | AMADORIASE AND METHOD FOR PRODUCING THE SAME, AGENT FOR IMPROVING SURFACTANT RESISTANCE OF AMADORIASE AND COMPOSITION FOR MEASURING HBA1C USING THE SAME | Kikkoman Corporation (JP) | 2021-01-06 | — | — | EP | disclosed |
| EP-3031914-B1 | MODIFIED AMADORIASE AND METHOD FOR PRODUCING THE SAME, AGENT FOR IMPROVING SURFACTANT RESISTANCE OF AMADORIASE AND COMPOSITION FOR MEASURING HBA1C USING THE SAME | KIKKOMAN CORP (JP) | 2020-12-23 | — | — | EP | disclosed |
| US-20200263228-A1 | MODIFIED AMADORIASE AND METHOD FOR PRODUCING THE SAME, AGENT FOR IMPROVING SURFACTANT RESISTANCE OF AMADORIASE AND COMPOSITION FOR MEASURING HbA1c USING THE SAME | KIKKOMAN CORPORATION (JP) | 2020-08-20 | — | — | US | disclosed |
| US-20120264758-A1 | ANTIMICROBIAL SOLUTIONS AND PROCESS RELATED THERETO | BYOCOAT ENTERPRISES, INC. (US) | 2012-10-18 | — | — | US | disclosed |
| US-20110281002-A1 | ANTIMICROBIAL SOLUTIONS AND PROCESS RELATED THERETO | BYOCOAT ENTERPRISES, INC. (PR) | 2011-11-17 | — | — | US | disclosed |
| US-20090192165-A1 | ANTIMICROBIAL SOLUTIONS AND PROCESS RELATED THERETO | BYOCOAT ENTERPRISES, INC. (PR) | 2009-07-30 | — | — | US | disclosed |
| EP-1931209-A1 | ANTIMICROBIAL SOLUTIONS AND PROCESS RELATED THERETO | Byocoat Enterprises, Inc. (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2008008362-A2 | COMPOSITIONS AND METHODS FOR REDUCING OR PREVENTING MICROORGANISM GROWTH OR SURVIVAL IN AQUEOUS ENVIRONMENTS | BYOCOAT ENTERPRISES, INC. (US) | 2008-01-17 | — | — | WO | disclosed |
| WO-2007030104-A1 | ANTIMICROBIAL SOLUTIONS AND PROCESS RELATED THERETO | BYOCOAT ENTERPRISES, INC. (US) | 2007-03-15 | — | — | WO | disclosed |
| US-20060110506-A1 | Antimicrobial solutions and process related thereto | BYOCOAT ENTERPRISES, INC. | 2006-05-25 | — | — | US | disclosed |
| US-20050271781-A1 | Antimicrobial solutions and process related thereto | BYOCOAT ENTERPRISES, INC. | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110281002-A1 | ANTIMICROBIAL SOLUTIONS AND PROCESS RELATED THERETO | DAO, AGPS, TH | ACHE 1327/4885CHRM2 3847/4885CHRM1 3574/4885 |
| US-20090192165-A1 | ANTIMICROBIAL SOLUTIONS AND PROCESS RELATED THERETO | DAO, AGPS, DDC | ACHE 2330/4885CHRM2 4551/4885CHRM1 4428/4885 |
| US-20120264758-A1 | ANTIMICROBIAL SOLUTIONS AND PROCESS RELATED THERETO | DAO, AGPS, DDC | ACHE 2330/4885CHRM2 4551/4885CHRM1 4428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.