Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.41 |
| ▸ | CA1 | P00915 | 8/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | CA5A | P35218 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 3/20 | 0.41 |
| ▸ | CA6 | P23280 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6917671 | 0.87 | FABP4 (0.44) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL28022942 | 0.86 | CA2 (0.40) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL8976123 | 0.84 | CA2 (0.52) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL6111777 | 0.82 | CA2 (0.39) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL26669292 | 0.82 | FABP4 (0.36) | CA2CA1CA9CA5ACA12 | |
| Trifluoroacetic Acid SCHEMBL28022384 | 0.80 | FABP4 (0.38) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL7696392 | 0.80 | CA2 (0.41) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL8770175 | 0.78 | SCN9A (0.42) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL7086924 | 0.78 | CA12 (0.38) | CA2CA1CA9CA12CA7 | |
| SCHEMBL7086922 | 0.78 | CA12 (0.38) | CA2CA1CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794942-A1 | SUBSTITUTED BIPHENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996016934-A1 | SUBSTITUTED BIPHENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-06-06 | — | — | WO | disclosed |