Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL28022384

NS(=O)(=O)c1ccc(C(F)(F)F)c(-c2ccccc2)c1Cl.O=C(O)C(F)(F)F

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 1/20 0.38
PRSS1 P07477 7/20 0.37
PRSS2 P07478 6/20 0.37
PRSS3 P35030 6/20 0.37
F10 P00742 4/20 0.37
CA2 P00918 7/20 0.36
CA7 P43166 4/20 0.36
CA1 P00915 6/20 0.35
CA9 Q16790 3/20 0.35
CA12 O43570 2/20 0.35
CA4 P22748 2/20 0.35
CA6 P23280 2/20 0.35
CA5A P35218 2/20 0.35
CA14 Q9ULX7 2/20 0.35
CA5B Q9Y2D0 2/20 0.35
PTGS2 P35354 1/20 0.35
CA3 P07451 1/20 0.35
CA13 Q8N1Q1 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
F2 P00734 5/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28022942 0.93 CA2 (0.40) FABP4CA2CA7CA1CA9
SCHEMBL8770178 0.80 CA2 (0.41) FABP4CA2CA7CA1CA9
SCHEMBL28022924 0.76 KIF11 (0.42) FABP4PTGS2
Trifluoroacetic Acid SCHEMBL15918323 0.75 KMT2A (0.49) CA2CA7CA1CA9CA12
SCHEMBL6917671 0.74 FABP4 (0.44) FABP4CA2CA7CA1CA9
SCHEMBL6111777 0.73 CA2 (0.39) FABP4CA2CA7CA1CA9
SCHEMBL26669292 0.73 FABP4 (0.36) FABP4CA2CA7CA1CA9
SCHEMBL7508828 0.72 CA2 (0.46) CA2CA7CA1CA9CA12
Trifluoroacetic Acid SCHEMBL15924604 0.71 PRSS1 (0.55) PRSS1PRSS2PRSS3F10F2
SCHEMBL28022377 0.71 CA2 (0.40) CA2CA1CA9CA12CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105102449-A Antiviral compounds HOFFMANN LA ROCHE 2015-11-25 CN disclosed