Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770708 | 0.88 | PTGDR2 (0.47) | PTGDR2ALDH1A1HTTMAPTLMNA | |
| SCHEMBL12838161 | 0.85 | KMT2A (0.49) | RAB9AALDH1A1HTTL3MBTL1GAA | |
| SCHEMBL6984076 | 0.85 | MAPT (0.59) | RAB9AALDH1A1GAAMAPTLMNA | |
| SCHEMBL13623312 | 0.85 | PTGDR2 (0.44) | RAB9APTGDR2ALDH1A1HTTMAPT | |
| SCHEMBL4861216 | 0.83 | S1PR4 (0.53) | S1PR4RAB9APTGDR2ALDH1A1GAA | |
| SCHEMBL2947864 | 0.81 | LMNA (0.45) | RAB9APTGDR2ALDH1A1GAAMAPT | |
| SCHEMBL6609945 | 0.79 | MTNR1A (0.49) | RAB9AALDH1A1HTTL3MBTL1GAA | |
| SCHEMBL24934106 | 0.79 | AAK1 (0.40) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL8770380 | 0.79 | AAK1 (0.40) | PTGDR2ALDH1A1HTTMAPTSMN1; SMN2 | |
| SCHEMBL24933585 | 0.79 | AAK1 (0.57) | RAB9APTGDR2ALDH1A1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632019-B1 | Acylureas | ZENECA LTD (GB) | 1997-09-24 | — | — | EP | disclosed |
| US-5576334-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1996-11-19 | — | — | US | disclosed |
| EP-0632019-A1 | Acylureas | ZENECA LIMITED (GB) | 1995-01-04 | — | — | EP | disclosed |