Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12838161 | 0.93 | KMT2A (0.49) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8770253 | 0.88 | S1PR4 (0.49) | PTGDR2MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13623312 | 0.88 | PTGDR2 (0.44) | PTGDR2MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6984076 | 0.88 | MAPT (0.59) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL2947864 | 0.85 | LMNA (0.45) | PTGDR2MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7363912 | 0.84 | PTGS2 (0.57) | PTGDR2MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL655716 | 0.81 | PTGS2 (0.60) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL13215543 | 0.81 | POLB (0.42) | PTGDR2MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13215153 | 0.80 | POLB (0.57) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL6478841 | 0.80 | CHRNB2 (0.52) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632019-B1 | Acylureas | ZENECA LTD (GB) | 1997-09-24 | — | — | EP | disclosed |
| US-5576334-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1996-11-19 | — | — | US | disclosed |
| EP-0632019-A1 | Acylureas | ZENECA LIMITED (GB) | 1995-01-04 | — | — | EP | disclosed |