Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770324 | 0.87 | KMT2A (0.42) | ITGB3ITGA2BKMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL8770179 | 0.84 | ITGB3 (0.74) | ITGB3ITGA2BKMT2A | |
| SCHEMBL8770307 | 0.84 | ITGB3 (0.60) | ITGB3ITGA2BKMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL8770319 | 0.80 | KMT2A (0.43) | KMT2ASMN1; SMN2ALOX15HTTFASN | |
| SCHEMBL8770635 | 0.73 | ITGB3 (0.44) | ITGB3ITGA2BKMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL8382676 | 0.73 | ITGB3 (0.57) | ITGB3ITGA2B | |
| SCHEMBL8382672 | 0.73 | ITGB3 (0.57) | ITGB3ITGA2B | |
| SCHEMBL8770650 | 0.73 | ITGB3 (0.55) | ITGB3ITGA2BKMT2A | |
| SCHEMBL8379238 | 0.72 | ITGB3 (0.73) | ITGB3ITGA2BKMT2AFASN | |
| SCHEMBL8379235 | 0.72 | ITGB3 (0.73) | ITGB3ITGA2BKMT2AFASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632019-B1 | Acylureas | ZENECA LTD (GB) | 1997-09-24 | — | — | EP | disclosed |
| US-5576334-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1996-11-19 | — | — | US | disclosed |
| EP-0632019-A1 | Acylureas | ZENECA LIMITED (GB) | 1995-01-04 | — | — | EP | disclosed |