Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770620 | 0.87 | ITGB3 (0.55) | KMT2AITGB3ITGA2BFASNHRH2 | |
| SCHEMBL8770650 | 0.86 | ITGB3 (0.55) | KMT2AITGB3ITGA2B | |
| SCHEMBL8770635 | 0.86 | ITGB3 (0.44) | KMT2AITGB3ITGA2BSMN1; SMN2ALOX15 | |
| SCHEMBL8770319 | 0.79 | KMT2A (0.43) | KMT2ANAMPTFASNHRH2HRH1 | |
| SCHEMBL7296779 | 0.73 | ITGB3 (0.54) | KMT2AITGB3ITGA2BSMN1; SMN2KDM4E | |
| SCHEMBL8770297 | 0.72 | ITGB3 (0.53) | ITGB3ITGA2B | |
| SCHEMBL8719948 | 0.72 | KDM1A (0.49) | FASNHRH2HRH1ALDH1A1SIGMAR1 | |
| SCHEMBL8770307 | 0.71 | ITGB3 (0.60) | KMT2AITGB3ITGA2BSMN1; SMN2ALOX15 | |
| SCHEMBL8770179 | 0.71 | ITGB3 (0.74) | KMT2AITGB3ITGA2B | |
| SCHEMBL21070287 | 0.71 | ALDH1A1 (0.40) | KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632019-B1 | Acylureas | ZENECA LTD (GB) | 1997-09-24 | — | — | EP | disclosed |
| US-5576334-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1996-11-19 | — | — | US | disclosed |
| EP-0632019-A1 | Acylureas | ZENECA LIMITED (GB) | 1995-01-04 | — | — | EP | disclosed |