Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770629 | 0.84 | KMT2A (0.44) | KMT2ASMN1; SMN2HTTALOX15ALDH1A1 | |
| SCHEMBL8770643 | 0.84 | ITGB3 (0.50) | KMT2ASMN1; SMN2HTTALOX15 | |
| SCHEMBL8770620 | 0.80 | ITGB3 (0.55) | KMT2ASMN1; SMN2HTTALOX15FASN | |
| SCHEMBL8770324 | 0.79 | KMT2A (0.42) | KMT2ASMN1; SMN2HTTALOX15FASN | |
| SCHEMBL30250401 | 0.71 | GAA (0.48) | KMT2ASMN1; SMN2HTTALOX15NPC1 | |
| Hydrochloric Acid SCHEMBL29268514 | 0.70 | GAA (0.47) | KMT2ASMN1; SMN2HTTALOX15NPC1 | |
| SCHEMBL28363614 | 0.68 | TDP1 (0.70) | KMT2ASMN1; SMN2HTTALDH1A1KDM4E | |
| SCHEMBL7296779 | 0.67 | ITGB3 (0.54) | KMT2ASMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL3254358 | 0.67 | L3MBTL1 (0.43) | KMT2AALOX15ALDH1A1LMNA | |
| SCHEMBL8770310 | 0.66 | SMN1; SMN2 (0.60) | KMT2ASMN1; SMN2HTTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632019-B1 | Acylureas | ZENECA LTD (GB) | 1997-09-24 | — | — | EP | disclosed |
| US-5576334-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1996-11-19 | — | — | US | disclosed |
| EP-0632019-A1 | Acylureas | ZENECA LIMITED (GB) | 1995-01-04 | — | — | EP | disclosed |