Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.38 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770650 | 0.90 | ITGB3 (0.55) | ITGB3ITGA2BKMT2AF2PLG | |
| SCHEMBL8770324 | 0.86 | KMT2A (0.42) | ITGB3ITGA2BKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8770307 | 0.86 | ITGB3 (0.60) | ITGB3ITGA2BKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8770629 | 0.78 | KMT2A (0.44) | ITGB3ITGA2BKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8770297 | 0.76 | ITGB3 (0.53) | ITGB3ITGA2BF2PLGPRSS1 | |
| SCHEMBL8770179 | 0.76 | ITGB3 (0.74) | ITGB3ITGA2BKMT2AF2PLG | |
| SCHEMBL8770620 | 0.73 | ITGB3 (0.55) | ITGB3ITGA2BKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL21070287 | 0.71 | ALDH1A1 (0.40) | KMT2AALDH1A1SMN1; SMN2TDP1POLB | |
| SCHEMBL24869858 | 0.69 | KMT2A (0.41) | KMT2AALDH1A1 | |
| SCHEMBL7011243 | 0.68 | SMN1; SMN2 (0.57) | KMT2AALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632019-B1 | Acylureas | ZENECA LTD (GB) | 1997-09-24 | — | — | EP | disclosed |
| US-5576334-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1996-11-19 | — | — | US | disclosed |
| EP-0632019-A1 | Acylureas | ZENECA LIMITED (GB) | 1995-01-04 | — | — | EP | disclosed |